Revealing the Structural Basis of Promiscuous Amine Transaminase Activity

被引：82

作者：

Steffen-Munsberg, Fabian ^{[1
]}

Vickers, Clare ^{[1
]}

Thontowi, Ahmad ^{[1
]}

Schaetzle, Sebastian ^{[1
]}

Meinhardt, Tina ^{[1
]}

Humble, Maria Svedendahl ^{[2
]}

Land, Henrik ^{[3
]}

Berglund, Per ^{[3
]}

Bornscheuer, Uwe T. ^{[1
]}

Hoehne, Matthias ^{[1
]}

机构：

[1] Inst Biochem, D-17487 Greifswald, Germany

[2] Stockholm Univ, Dept Organ Chem, Arrhenius Labs, SE-10691 Stockholm, Sweden

[3] AlbaNova Univ Ctr, Sch Biotechnol, KTH Royal Inst Technol, S-10691 Stockholm, Sweden

来源：

CHEMCATCHEM | 2013年 / 5卷 / 01期

关键词：

amines; chirality; catalytic promiscuity; dual substrate recognition; enzyme catalysis; CRYSTAL-STRUCTURES; SUBSTRATE RECOGNITION; ENZYME PROMISCUITY; AMINOTRANSFERASE; PYRUVATE; BIOCATALYSIS; LOCALIZATION; SPECIFICITY; GLYOXYLATE; EXPRESSION;

D O I：

10.1002/cctc.201200545

中图分类号：

O64 [物理化学（理论化学）、化学物理学];

学科分类号：

070304 ; 081704 ;

摘要：

[No abstract available]

引用

页码：154 / 157

页数：4

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