Maternal and fetal exposure to bisphenol A in Korea

被引：167

作者：

Lee, Young Joo ^{[1
]}

Ryu, Heui-Young ^{[1
]}

Kim, Hyun-Yung ^{[1
]}

Min, Chung Sik ^{[1
]}

Lee, Jin Hee ^{[1
]}

Kim, Eunhee ^{[1
]}

Nam, Bong Hyun ^{[1
]}

Park, Joo Hong ^{[1
]}

Jung, Jin Young ^{[1
]}

Jang, Dong Deuk ^{[1
]}

Park, Eun Young ^{[2
]}

Lee, Kwan-Hee ^{[3
]}

Ma, Jin-Young ^{[4
]}

Won, Hey-Sung ^{[4
]}

Im, Moon-Whan ^{[5
]}

Leem, Jong-Han ^{[3
]}

Hong, Yun-Chul ^{[2
]}

Yoon, Hae-Seong ^{[1
]}

机构：

[1] Korea Food & Drug Adm, Natl Inst Toxicol Res, Human Exposure Assessment Team, Seoul, South Korea

[2] Seoul Natl Univ, Coll Med, Dept Prevent Med, Seoul, South Korea

[3] Inha Univ Hosp, Dept Occupat & Environm Med, Inchon, South Korea

[4] Asan Med Ctr, Dept Obstet & Gynecol, Seoul, South Korea

[5] Inha Univ Hosp, Dept Obstet & Gynecol, Inchon, South Korea

来源：

REPRODUCTIVE TOXICOLOGY | 2008年 / 25卷 / 04期

关键词：

bisphenol A; human exposure; biomonitoring; pregnant woman; maternal serum; fetus; umbilical cord blood; Korea;

D O I：

10.1016/j.reprotox.2008.05.058

中图分类号：

Q [生物科学];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

Bisphenol A (BPA) is a well-known endocrine disrupter used widely. Despite the potential risk of human exposure to BPA, little information exists concerning maternal and fetal exposure to BPA during pregnancy in Korea. This study purposed to evaluate the correlation between maternal and fetal exposure, and to determine exposure levels to BPA in Korean pregnant women and their fetuses. Maternal blood and umbilical cord blood were collected from 300 subjects, and total BPA levels were measured. Blood BPA concentrations ranged from non-detectable to 66.48 mu g/L in pregnant women and from non-detectable to 8.86 mu g/L in umbilical cords. Serum BPA levels in most pregnant women were higher than in corresponding fetal umbilical cords and a positive correlation was found between in maternal and fetal BPA concentrations (p < 0.05). (C) 2008 Elsevier Inc. All rights reserved.

引用

页码：413 / 419

页数：7

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