Therapeutic Advancements in the Management of Diabetes Mellitus with Special Reference to Nanotechnology

被引:7
作者
Chauhan, Pallavi Singh [1 ]
Yadav, Dhananjay [2 ]
Tayal, Shivam [3 ]
Jin, Jun-O [2 ,4 ]
机构
[1] Amity Univ Madhya Pradesh, Amity Inst Biotechnol, Gwalior, Madhya Pradesh, India
[2] Yeungnam Univ, Dept Med Biotechnol, Gyongsan 712749, South Korea
[3] ITM Univ, Sch Pharm, Gwalior, Madhya Pradesh, India
[4] Yeungnam Univ, Res Inst Cell Culture, Gyongsan 38541, South Korea
基金
新加坡国家研究基金会;
关键词
Diabetes mellitus; nanotechnology; blood glucose sensors; nano drug therapy; diabetic complications; sensitivity; DELIVERY-SYSTEMS; NANOPARTICLES; GLUCOSE; SENSORS;
D O I
10.2174/1381612826666200826135401
中图分类号
R9 [药学];
学科分类号
1007 ;
摘要
For improvisation of diabetic's quality of life, nanotechnology is facilitating the development of advanced glucose sensors as well as efficient insulin delivery systems. Our prime focus of the review is to highlight the advancement in diabetic research with special reference to nanotechnology at its interface. Recent studies are more focused on enhancing sensitivity, accuracy, and response by employing metal as well as nanoparticles based glucose sensors. Moreover, the review focuses on nanoscale based approaches i.e. closed-loop insulin delivery systems, which detect any fluctuation in blood glucose levels and allow controlled release of a drug, thus are also called self-regulating insulin release system. Additionally, this review summarizes the role of nanotechnology in the diagnosis and treatment of diabetic complications through little advancement in the existing techniques. To improve health, as well as the quality of life in diabetic's new sensing systems for blood glucose level evaluation and controlled administration of drugs through efficient drug delivery systems should be explored.
引用
收藏
页码:4909 / 4916
页数:8
相关论文
共 98 条
[51]  
Marc G, 2019, MOLECULES, V24
[52]  
Mbanya Jean Claude, 2017, Eur Endocrinol, V13, P21, DOI 10.17925/EE.2017.13.01.21
[53]   Carbon Nanostructures as a Multi-Functional Platform for Sensing Applications [J].
Mendes, Rafael Gregorio ;
Wrobel, Pawel S. ;
Bachmatiuk, Alicja ;
Sun, Jingyu ;
Gemming, Thomas ;
Liu, Zhongfan ;
Ruemmeli, Mark Hermann .
CHEMOSENSORS, 2018, 6 (04)
[54]   Carbon-Based Nanomaterials/Allotropes: A Glimpse of Their Synthesis, Properties and Some Applications [J].
Nasir, Salisu ;
Hussein, Mohd Zobir ;
Zainal, Zulkarnain ;
Yusof, Nor Azah .
MATERIALS, 2018, 11 (02)
[55]  
Nassar Joanna M., 2018, NPJ FLEX ELECTRON, V2, DOI [10.1038/s41528-018-0025-1, DOI 10.1038/S41528-018-0025-1]
[56]   Current progress in application of polymeric nanofibers to tissue engineering [J].
Nemati, Sorour ;
Kim, Se-jeong ;
Shin, Young Min ;
Shin, Heungsoo .
NANO CONVERGENCE, 2019, 6 (01)
[57]   Transdermal drug delivery systems in diabetes management: A review [J].
Ng, Li Ching ;
Gupta, Manish .
ASIAN JOURNAL OF PHARMACEUTICAL SCIENCES, 2020, 15 (01) :13-25
[58]   Trends in the pervasiveness of type 2 diabetes, impaired fasting glucose and co-morbidities during an 8-year-follow-up of nationwide Korean population [J].
Noh, Junghyun ;
Han, Kyung-Do ;
Ko, Seung-Hyun ;
Ko, Kyung Soo ;
Park, Cheol-Young .
SCIENTIFIC REPORTS, 2017, 7
[59]   Chitosan enhances nanoparticle delivery from the reproductive tract to target draining lymphoid organs [J].
Park, Jaehyung ;
Ramanathan, Renuka ;
Pham, Linhchi ;
Woodrow, Kim A. .
NANOMEDICINE-NANOTECHNOLOGY BIOLOGY AND MEDICINE, 2017, 13 (06) :2015-2025
[60]   Nano based drug delivery systems: recent developments and future prospects [J].
Patra, Jayanta Kumar ;
Das, Gitishree ;
Fraceto, Leonardo Fernandes ;
Ramos Campos, Estefania Vangelie ;
del Pilar Rodriguez-Torres, Maria ;
Susana Acosta-Torres, Laura ;
Armando Diaz-Torres, Luis ;
Grillo, Renato ;
Swamy, Mallappa Kumara ;
Sharma, Shivesh ;
Habtemariam, Solomon ;
Shin, Han-Seung .
JOURNAL OF NANOBIOTECHNOLOGY, 2018, 16