Failure to Validate a Multivariable Clinical Prediction Model to Identify Pediatric Intensive Care Unit Patients at High Risk for Candidemia

被引：10

作者：

Fisher, Brian T. ^{[1
,2
,3
,4
]}

Ross, Rachael K. ^{[1
,2
]}

Roilides, Emmanuel ^{[5
,6
]}

Palazzi, Debra L. ^{[7
,8
]}

Abzug, Mark J. ^{[9
,10
]}

Hoffman, Jill A. ^{[11
]}

Berman, David M. ^{[12
]}

Prasad, Priya A. ^{[13
]}

Localio, A. Russell ^{[2
,3
,4
]}

Steinbach, William J. ^{[14
]}

Vogiatzi, Lambrini ^{[15
]}

Dutta, Ankhi ^{[7
,8
]}

Zaoutis, Theoklis E. ^{[1
,2
,3
,4
]}

机构：

[1] Childrens Hosp Philadelphia, Div Infect Dis, Philadelphia, PA 19104 USA

[2] Childrens Hosp Philadelphia, Ctr Pediat Clin Effectiveness, Philadelphia, PA 19104 USA

[3] Univ Penn, Dept Pediat, Perelman Sch Med, Philadelphia, PA 19104 USA

[4] Univ Penn, Ctr Clin Epidemiol & Biostat, Perelman Sch Med, Philadelphia, PA 19104 USA

[5] Aristotle Univ Thessaloniki, Sch Hlth Sci, Dept Pediat 3, Infect Dis Unit, Thessaloniki, Greece

[6] Hippokrateion Hosp, Thessaloniki, Greece

[7] Baylor Coll Med, Dept Pediat, Infect Dis Sect, Houston, TX 77030 USA

[8] Texas Childrens Hosp, Houston, TX 77030 USA

[9] Univ Colorado, Sch Med, Boulder, CO 80309 USA

[10] Childrens Hosp Colorado, Aurora, CO USA

[11] Univ Southern Calif, Keck Sch Med, Childrens Hosp Los Angeles, Los Angeles, CA USA

[12] All Childrens Hosp, St Petersburg, FL USA

[13] Univ Calif San Francisco, Dept Epidemiol & Biostat, San Francisco, CA 94143 USA

[14] Duke Univ, Med Ctr, Dept Pediat, Div Pediat Infect Dis, Durham, NC 27710 USA

[15] Hippokrateion Hosp, Pediat Intens Care Unit, Thessaloniki, Greece

来源：

JOURNAL OF THE PEDIATRIC INFECTIOUS DISEASES SOCIETY | 2016年 / 5卷 / 04期

关键词：

candidemia; ICU; pediatric; prediction; validation; INVASIVE CANDIDIASIS; CHILDREN; EPIDEMIOLOGY; RULES;

D O I：

10.1093/jpids/piv024

中图分类号：

R51 [传染病];

学科分类号：

100401 ;

摘要：

We attempted to validate a previously derived clinical prediction rule for candidemia in the pediatric intensive care unit. This multicenter case control study did not identify significant association of candidemia with most of the previously identified predictors. Additional study in larger cohorts with other predictor variables is needed.

引用

页码：458 / 461

页数：4

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