Assessment of Disease Severity and Quality of Life in Patients with Atopic Dermatitis from South Korea

被引：6

作者：

Son, Sang Wook ^{[1
]}

Lee, Ji Hyun ^{[2
]}

Ahn, Jiyoung ^{[3
]}

Chang, Sung Eun ^{[4
,5
]}

Choi, Eung Ho ^{[6
]}

Han, Tae Young ^{[7
]}

Jang, Yong Hyun ^{[8
]}

Kim, Hye One ^{[9
]}

Kim, Moon-Bum ^{[10
]}

Kim, You Chan ^{[11
]}

Ko, Hyun Chang ^{[12
]}

Ko, Joo Yeon ^{[13
]}

Lee, Sang Eun ^{[14
,15
]}

Lee, Yang Won ^{[16
]}

Lew, Bark-Lynn ^{[17
]}

Na, Chan Ho ^{[18
]}

Park, Chang Ook ^{[19
,20
]}

Park, Chun Wook ^{[9
]}

Park, Kui Young ^{[21
]}

Park, Kun ^{[22
]}

Park, Young Lip ^{[23
]}

Roh, Joo Young ^{[24
,29
]}

Seo, Young-Joon ^{[25
]}

Shin, Min Kyung ^{[26
]}

Lee, Sujin ^{[27
]}

Cho, Sang Hyun ^{[28
]}

机构：

[1] Korea Univ, Coll Med, Dept Dermatol, Ansan Hosp, Ansan, South Korea

[2] Catholic Univ Korea, Coll Med, Dept Dermatol, Seoul St Marys Hosp, Seoul, South Korea

[3] Natl Med Ctr, Dept Dermatol, Seoul, South Korea

[4] Univ Ulsan, Asan Med Ctr, Dept Dermatol, Coll Med, Seoul, South Korea

[5] Univ Ulsan, Asan Med Ctr, Res Inst Dermatol, Coll Med, Seoul, South Korea

[6] Yonsei Univ, Wonju Severance Christian Hosp, Dept Dermatol, Wonju Coll Med, Wonju, South Korea

[7] Eulji Univ, Nowon Eulji Med Ctr, Dept Dermatol, Seoul, South Korea

[8] Kyungpook Natl Univ, Kyungpook Natl Univ Hosp, Sch Med, Dept Dermatol, Daegu, South Korea

[9] Hallym Univ, Dept Dermatol, Kangnam Sacred Heart Hosp, Seoul, South Korea

[10] Pusan Natl Univ Hosp, Dept Dermatol, Busan, South Korea

[11] Ajou Univ, Ajou Univ Hosp, Dept Dermatol, Sch Med, Suwon, South Korea

[12] Pusan Natl Univ, Yangsan Hosp, Sch Med, Dept Dermatol, Yangsan, South Korea

[13] Hanyang Univ, Coll Med, Dept Dermatol, Seoul Hosp, Seoul, South Korea

[14] Yonsei Univ, Gangnam Severance Hosp, Dept Dermatol, Coll Med, Seoul, South Korea

[15] Yonsei Univ, Gangnam Severance Hosp, Cutaneous Biol Res Inst, Coll Med, Seoul, South Korea

[16] Konkuk Univ, Dept Dermatol, Sch Med, Seoul, South Korea

[17] Kyung Hee Univ, Kyung Hee Univ Hosp Gangdong, Dept Dermatol, Coll Med, Seoul, South Korea

[18] Chosun Univ, Chosun Univ Hosp, Coll Med, Dept Dermatol, Gwangju, South Korea

[19] Yonsei Univ, Severance Hosp, Dept Dermatol, Coll Med, Seoul, South Korea

[20] Yonsei Univ, Severance Hosp, Cutaneous Biol Res Inst, Coll Med, Seoul, South Korea

[21] Chung Ang Univ, Chung Ang Univ Hosp, Dept Dermatol, Coll Med, Seoul, South Korea

[22] Wonkwang Univ Hosp, Dept Dermatol, Iksan, South Korea

[23] Soonchunhyang Univ, Dept Dermatol, Bucheon Hosp, Bucheon, South Korea

[24] Gachon Univ, Gil Med Ctr, Dept Dermatol, Coll Med, Incheon, South Korea

[25] Chungnam Natl Univ Hosp, Dept Dermatol, Daejeon, South Korea

[26] Kyung Hee Univ, Kyung Hee Univ Hosp, Coll Med, Dept Dermatol, Seoul, South Korea

[27] Sanofi Aventis Korea Co Ltd, Med Affairs, Seoul, South Korea

[28] Catholic Univ Korea, Coll Med, Dept Dermatol, Incheon St Marys Hosp, 56 Dongsu Ro, Seoul 21431, South Korea

[29] Ewha Womans Univ, Dept Dermatol, Seoul Hosp, Seoul, South Korea

来源：

ANNALS OF DERMATOLOGY | 2022年 / 34卷 / 06期

关键词：

Anxiety; Atopic dermatitis; Depression; Quality of life; MODERATE; MANAGEMENT; DERMATOLOGY; CONSENSUS; HEALTH; GUIDELINES; ADULTS; AREA;

D O I：

10.5021/ad.21.239

中图分类号：

R75 [皮肤病学与性病学];

学科分类号：

100206 ;

摘要：

Background: Data illustrating the impact of atopic dermatitis (AD) on lives of adults with AD in South Korea are limited. Objective: To assess the AD disease severity and its impact on quality of life (QoL) in patients with AD from South Korea. Methods: Patients with AD utilizing the specialist dermatology services of major hospitals in South Korea were assessed for disease severity using Eczema Area and Severity Index (EASI) score, for QoL using Dermatology Life Quality Index (DLQI) (for QoL), and for comorbidities and treatment experience via retrospective review of 12-month medical records. Clinical and sociodemographic characteristics were also measured. Results: Of the 1,163 patients, 695 (59.8%) were men (mean age [years]+/- standard deviation: 31.6 +/- 12.1). Overall, 52.9% (n=615) patients had moderate-to-severe disease (EASI>7). The QoL of 72.3% (n=840) patients was affected moderately-to-severely (DLQI score: 6 similar to 30). Systemic immunosuppressants were used >= 1 over past 12 months in 51.9% (n=603) patients, and the most commonly used were cyclosporines (45.7%, n=531) and systemic corticosteroids (40.5%, n= 471). Approximately, 10.8% (n=126) patients consulted or received treatment for AD-related eye problem. Of these, 40% (n=50) patients reported poor, very poor, or completely blind status; approximately, 16.7% patients (n=192) reported having depression or anxiety; and 35.5% (n=410) reported suicidal ideation or suicidal attempt. Conclusion: A large proportion of patients had moderate-to-severe AD, a compromised QoL, and ocular or mental health comorbidities, indicating a high disease burden despite systemic treatment. These findings highlight the importance of a holistic approach for the evaluation and treatment of patients with AD.

引用

页码：419 / 430

页数：12

共 26 条

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