Comparison of microwave-assisted and conventional extraction of mangiferin from mango (Mangifera indica L.) leaves

被引:47
作者
Zou, Tangbin [1 ]
Wu, Hongfu [2 ]
Li, Huawen [1 ]
Jia, Qing [1 ]
Song, Gang [1 ]
机构
[1] Guangdong Med Coll, Sch Publ Hlth, Dept Nutr & Food Hyg, Dongguan 523808, Peoples R China
[2] Guangdong Med Coll, Sch Basic Med Sci, Dept Physiol, Dongguan 523808, Peoples R China
关键词
Mangiferin; Mango leaves; Microwave-assisted extraction; Response surface methodology; RESPONSE-SURFACE METHODOLOGY; LIQUID-LIQUID MICROEXTRACTION; ANTIOXIDANT ACTIVITY; MASS-SPECTROMETRY; OPTIMIZATION; CHROMATOGRAPHY; POLYPHENOLS; KERNEL; ACIDS; BARK;
D O I
10.1002/jssc.201300518
中图分类号
O65 [分析化学];
学科分类号
070302 ; 081704 ;
摘要
Mangiferin is the main bioactive component in mango leaves, which possesses anti-inflammatory, antioxidative, antidiabetic, immunomodulatory, and antitumor activities. In the present study, a microwave-assisted extraction method was developed for the extraction of mangiferin from mango leaves. Some parameters such as ethanol concentration, liquid-to-solid ratio, microwave power, and extraction time were optimized by single-factor experiments and response surface methodology. The optimal extraction conditions were 45% ethanol, liquid-to-solid ratio of 30:1 (mL/g), and extraction time of 123 s under microwave irradiation of 474 W. Under optimal conditions, the yield of mangiferin was 36.10 +/- 0.72 mg/g, significantly higher than that of conventional extraction. The results obtained are beneficial for the full utilization of mango leaves and also indicate that microwave-assisted extraction is a very useful method for extracting mangiferin from plant materials.
引用
收藏
页码:3457 / 3462
页数:6
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