Classification of acute and delayed contrast media-induced reactions: proposal of a three-step system

被引:21
作者
Boehm, Ingrid [1 ]
Heverhagen, Johannes T. [1 ]
Klose, Klaus J. [1 ]
机构
[1] Univ Marburg, Dept Diagnost Radiol, D-35033 Marburg, Germany
关键词
contrast medium; personalized medicine; immediate reaction; nonimmediate reaction; LATE ADVERSE-REACTIONS; TOXIC EPIDERMAL NECROLYSIS; ALLERGY-LIKE REACTIONS; HYPERSENSITIVITY REACTIONS; RADIOCONTRAST MEDIA; ANAPHYLAXIS; IODINE; AGENTS; NOMENCLATURE; PREVENTION;
D O I
10.1002/cmmi.1475
中图分类号
R8 [特种医学]; R445 [影像诊断学];
学科分类号
1002 ; 100207 ; 1009 ;
摘要
Physicians and scientists use a broad spectrum of terms to classify contrast media (CM)-induced adverse reactions. In particular, the designation of hypersensitivity reactions is quite varied. Consequently, comparisons of different papers dealing with this subject are difficult or even impossible. Moreover, general descriptions may lead to problems in understanding reactions in patients with a history of adverse CM-reactions, and in efficiently managing these patients. Therefore, the goal of this paper is to suggest an easy system to clearly classify these reactions. The proposed three-step systems (3SS) is built up as follows: step 1 exactly describes the clinical features, including their severity; step 2 categorizes the time point of the onset (immediate or nonimmediate); and step 3 generally classifies the reaction (hypersensitivity or nonhypersensitivity reaction). The 3SS may facilitate better understanding of the clinical manifestations of adverse CM reactions and may support the prevention of these reactions on the basis of personalized medicine approaches. Copyright (c) 2012 John Wiley & Sons, Ltd.
引用
收藏
页码:537 / 541
页数:5
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