Synthesis of fluorescent probes for the detection of abasic sites in DNA

被引：52

作者：

Boturyn, D ^{[1
]}

Boudali, A ^{[1
]}

Constant, JF ^{[1
]}

Defrancq, E ^{[1
]}

Lhomme, J ^{[1
]}

机构：

[1] UNIV GRENOBLE 1,UMR CNRS 5616,LEDSS,F-38041 GRENOBLE 9,FRANCE

来源：

TETRAHEDRON | 1997年 / 53卷 / 15期

关键词：

D O I：

10.1016/S0040-4020(97)00235-4

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The three luminescent molecules 1-3 were prepared as highly sensitive and specific probes for the quantification of a major DNA lesion, the abasic site. These molecules incorporate in their structure the reactive oxyamino function linked to the Dansyl or Lissamine-Rhodamine fluorophores through amido or polyether chains. (C) 1997 Elsevier Science Ltd.

引用

页码：5485 / 5492

页数：8

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