Prevalence and configuration of pulmonary nodules on multi-row CT in children without malignant diseases

被引:19
作者
Renne, Julius [1 ]
Linderkamp, Christin [2 ]
Wacker, Frank [1 ]
Berthold, Lars-Daniel [1 ]
Weidemann, Juergen [1 ]
机构
[1] Hannover Med Sch, Inst Diagnost & Intervent Radiol, D-30625 Hannover, Germany
[2] Hannover Med Sch, Pediat Oncol, D-30625 Hannover, Germany
关键词
Solitary pulmonary nodule; Child; Lung; Multidetector computed tomography; Neoplasms; INTRAPULMONARY LYMPH-NODES; COMPUTED-TOMOGRAPHY; SOLID TUMORS; FEATURES; BENIGN; SCANS;
D O I
10.1007/s00330-015-3675-6
中图分类号
R8 [特种医学]; R445 [影像诊断学];
学科分类号
1002 ; 100207 ; 1009 ;
摘要
Objectives To assess the prevalence and morphologic characterization of pulmonary nodules in children on a chest computed tomography (CT). Methods Two hundred and fifty-nine trauma chest CTs in children aged 0-18 years were retrospectively reviewed by two radiologists, each with more than 10 years of experience. Images were acquired on a 64-row CT. Pulmonary lobes with trauma affections such as contusion or haemorrhage were excluded. All pulmonary nodules were evaluated for distance from the pleural surface, location, calcification and size on axial slices. Results A total of 1,190/1,295 (92 %) pulmonary lobes without traumatic injury were included in this study. In 86 of 259 (33 %) patients, 131 pulmonary nodules were detected. Number of nodules per patient ranged from 1 to 4. Calcifications were seen in 19 % (25) of all nodules. Diameters ranged from 1 to 5 mm. 59 % (77) were located in the lower lobes, 9 % (12) in the middle lobe and 32 % (42) in the upper lobes. 84 % of the non-calcified nodules > 2 mm showed a slightly angular or triangular (mostly pleural nodes) shape. Conclusions Pulmonary nodules smaller than 5 mm can be detected frequently in children without malignant disease and are predominantly located in the lower lobes.
引用
收藏
页码:2651 / 2656
页数:6
相关论文
共 19 条
[1]   Pulmonary nodules discovered during the initial evaluation of pediatric patients with bone and soft-tissue sarcoma [J].
Absalon, Michael J. ;
McCarville, M. Beth ;
Liu, Tiebin ;
Santana, Victor A. ;
Daw, Najat C. ;
Navid, Fariba .
PEDIATRIC BLOOD & CANCER, 2008, 50 (06) :1147-1153
[2]   Do characteristics of pulmonary nodules on computed tomography in children with known osteosarcoma help distinguish whether the nodules are malignant or benign? [J].
Brader, Peter ;
Abramson, Sara J. ;
Price, Anita P. ;
Ishill, Nicole M. ;
Emily, Zabor C. ;
Moskowitz, Chaya S. ;
La Quaglia, Michael P. ;
Ginsberg, Michelle S. .
JOURNAL OF PEDIATRIC SURGERY, 2011, 46 (04) :729-735
[3]   Pulmonary nodules resected at video-assisted thoracoscopic surgery: Etiology in 426 patients [J].
Ginsberg, MS ;
Griff, SK ;
Go, BD ;
Yoo, HH ;
Schwartz, LH ;
Panicek, DM .
RADIOLOGY, 1999, 213 (01) :277-282
[4]   Pulmonary hamartomas: CT pixel analysis for fat attenuation using radiologic-pathologic correlation [J].
Gleeson, Tadhg ;
Thiessen, Rennae ;
Hannigan, Ailish ;
Murphy, Darra ;
English, John C. ;
Mayo, John R. .
JOURNAL OF MEDICAL IMAGING AND RADIATION ONCOLOGY, 2013, 57 (05) :534-543
[5]   Clinical significance of pulmonary nodules detected by CT and Not CXR in patients treated for favorable histology Wilms tumor on national Wilms tumor studies-4 and-5: A report from the Children's Oncology Group [J].
Grundy, Paul E. ;
Green, Daniel M. ;
Dirks, Astrid C. ;
Berendt, Andrea E. ;
Breslow, Norman E. ;
Anderson, James R. ;
Dome, Jeffrey S. .
PEDIATRIC BLOOD & CANCER, 2012, 59 (04) :631-635
[6]   PULMONARY CALCIFICATION IN VIRAL PNEUMONIA [J].
JONES, EL ;
CAMERON, AH .
JOURNAL OF CLINICAL PATHOLOGY, 1969, 22 (03) :361-&
[7]   The calcified lung nodule: What does it mean [J].
Khan, Ali Nawaz ;
Al-Jahdali, Hamdan H. ;
Allen, Carolyn M. ;
Irion, Klaus L. ;
Al Ghanem, Sarah ;
Koteyar, Shyam Sunder .
ANNALS OF THORACIC MEDICINE, 2010, 5 (02) :67-79
[8]   Guidelines for management of small pulmonary nodules detected on CT scans: A statement from the Fleischner Society [J].
MacMahon, H ;
Austin, JHM ;
Gamsu, G ;
Herold, CJ ;
Jett, JR ;
Naidich, DP ;
Patz, EF ;
Swensen, SJ .
RADIOLOGY, 2005, 237 (02) :395-400
[9]   Distinguishing benign from malignant pulmonary nodules with helical chest CT in children with malignant solid tumors [J].
McCarville, MB ;
Lederman, HM ;
Santana, VM ;
Daw, NC ;
Shochat, SJ ;
Li, CS ;
Kaufman, RA .
RADIOLOGY, 2006, 239 (02) :514-520
[10]   Intrapulmonary lymph nodes: CT and pathological features [J].
Miyake, H ;
Yamada, Y ;
Kawagoe, T ;
Hori, Y ;
Mori, H ;
Yokoyama, S .
CLINICAL RADIOLOGY, 1999, 54 (10) :640-643