Recurrent granular cell tumor of the thyroid: a case report and literature review

被引：3

作者：

He, Yu-qin ^{[1
]}

Lu, Hai-zhen ^{[1
]}

Li, De-zhi ^{[1
]}

Chen, Mo-qi ^{[1
]}

Wang, Kai ^{[1
]}

Xu, Zhen-gang ^{[1
]}

Liu, Shao-yan ^{[1
]}

机构：

[1] Chinese Acad Med Sci & Peking Union Med Coll, Natl Clin Res Ctr Canc, Natl Canc Ctr, Canc Hosp, Beijing 100021, Peoples R China

来源：

BMC SURGERY | 2020年 / 20卷 / 01期

关键词：

Thyroid; Granular cell tumor; Recurrent; ASPIRATION-CYTOLOGY; GLAND; HEAD; NECK;

D O I：

10.1186/s12893-020-00814-8

中图分类号：

R61 [外科手术学];

学科分类号：

摘要：

Background Granular cell tumor (GCT) of the thyroid is a rare benign tumor of Schwann cell origin with a favorable prognosis and only 10 cases have been reported so far in scientific literature. The present case study describes the first case of recurrent thyroid GCT. Case presentation Our case describes a 20-year-old woman who had undergone lobectomy for GCT of the thyroid 4 years ago. Hematoxylin-eosin (HE) staining revealed that the lesion was composed of epithelioid cells with an abundance of eosinophilic granular cytoplasm. Immunohistochemical analysis showed that tumor cells tested positive for S-100 protein and negative for desmin. Both histological and immunohistochemical analyses supported the diagnosis of recurrent GCT of the thyroid. Conclusions Our case suggested that a tumor-free margin excision and post-operative follow-up are necessary for the treatment of GCT of the thyroid.

引用

页数：5

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