Skin Mucus of Marine Fish as a Source for the Development of Antimicrobial Agents

被引：44

作者：

Tiralongo, Francesco ^{[1
]}

Messina, Giuseppina ^{[1
]}

Lombardo, Bianca Maria ^{[1
]}

Longhitano, Lucia ^{[2
]}

Li Volti, Giovanni ^{[2
]}

Tibullo, Daniele ^{[2
]}

机构：

[1] Univ Catania, Dept Biol Geol & Environm Sci, Catania, Italy

[2] Univ Catania, Dept Biomed & Biotechnol Sci, Sect Biochem, Catania, Italy

来源：

FRONTIERS IN MARINE SCIENCE | 2020年 / 7卷

关键词：

skin fish mucus; marine fish; antimicrobial activity; elasmobrachii; teleostean fish; EPIDERMAL MUCUS; PARENTAL CARE; ANTIBACTERIAL; EXTRACTS; PARAMETERS; SECRETION; CELLS;

D O I：

10.3389/fmars.2020.541853

中图分类号：

X [环境科学、安全科学];

学科分类号：

08 ; 0830 ;

摘要：

Fish skin mucus is an important component of the innate immune mechanism and provides a first barrier against pathogens. Although several studies investigated and demonstrated the antimicrobial properties of skin mucus of fishes, most of them tested antimicrobial properties against marine microbial strains as potential use in aquaculture. Furthermore, most of these studies concerned freshwater species, and far less attention was given to skin mucus of marine fishes for potential application in human health and research toward its antimicrobial properties. This review outlines the importance of marine fishes as an important and effective source of antimicrobial drugs against several human pathogens, thus providing a highly available and low-cost tool to counteract clinical infections.

引用

页数：7

共 42 条

[1] CHANGES IN THE CONCENTRATION AND HISTOCHEMISTRY OF EPIDERMAL MUCOUS CELLS DURING THE ALEVIN AND FRY STAGES OF THE BROWN TROUT SALMO-TRUTTA [J].