Viruses carry antiviral cargo

被引:2
作者
Schoggins, John W. [1 ]
机构
[1] Univ Texas SW Med Ctr Dallas, Dept Microbiol, Dallas, TX 75390 USA
关键词
GMP-AMP SYNTHASE; PROTEINS; SENSOR; CGAMP; HIV;
D O I
10.1126/science.aad0942
中图分类号
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号
07 ; 0710 ; 09 ;
摘要
引用
收藏
页码:1166 / 1167
页数:2
相关论文
共 11 条
[1]   Cell intrinsic immunity spreads to bystander cells via the intercellular transfer of cGAMP [J].
Ablasser, Andrea ;
Schmid-Burgk, Jonathan L. ;
Hemmerling, Inga ;
Horvath, Gabor L. ;
Schmidt, Tobias ;
Latz, Eicke ;
Hornung, Veit .
NATURE, 2013, 503 (7477) :530-+
[2]   Viruses transfer the antiviral second messenger cGAMP between cells [J].
Bridgeman, A. ;
Maelfait, J. ;
Davenne, T. ;
Partridge, T. ;
Peng, Y. ;
Mayer, A. ;
Dong, T. ;
Kaever, V. ;
Borrow, P. ;
Rehwinkel, J. .
SCIENCE, 2015, 349 (6253) :1228-1232
[3]   Bacterial small-molecule signaling pathways [J].
Camilli, A ;
Bassler, BL .
SCIENCE, 2006, 311 (5764) :1113-1116
[4]   Cyclic GMP-AMP Synthase Is an Innate Immune Sensor of HIV and Other Retroviruses [J].
Gao, Daxing ;
Wu, Jiaxi ;
Wu, You-Tong ;
Du, Fenghe ;
Aroh, Chukwuemika ;
Yan, Nan ;
Sun, Lijun ;
Chen, Zhijian J. .
SCIENCE, 2013, 341 (6148) :903-906
[5]   Transmission of innate immune signaling by packaging of cGAMP in viral particles [J].
Gentili, Matteo ;
Kowal, Joanna ;
Tkach, Mercedes ;
Satoh, Takeshi ;
Lahaye, Xavier ;
Conrad, Cecile ;
Boyron, Marilyn ;
Lombard, Berangere ;
Durand, Sylvere ;
Kroemer, Guido ;
Loew, Damarys ;
Dalod, Marc ;
Thery, Clotilde ;
Manel, Nicolas .
SCIENCE, 2015, 349 (6253) :1232-1236
[6]   OAS proteins and cGAS: unifying concepts in sensing and responding to cytosolic nucleic acids [J].
Hornung, Veit ;
Hartmann, Rune ;
Ablasser, Andrea ;
Hopfner, Karl-Peter .
NATURE REVIEWS IMMUNOLOGY, 2014, 14 (08) :521-528
[7]   Viral and cellular mechanisms of the innate immune sensing of HIV [J].
Lahaye, Xavier ;
Manel, Nicolas .
CURRENT OPINION IN VIROLOGY, 2015, 11 :55-62
[8]   Pivotal Roles of cGAS-cGAMP Signaling in Antiviral Defense and Immune Adjuvant Effects [J].
Li, Xiao-Dong ;
Wu, Jiaxi ;
Gao, Daxing ;
Wang, Hua ;
Sun, Lijun ;
Chen, Zhijian J. .
SCIENCE, 2013, 341 (6152) :1390-1394
[9]   Cellular proteins detected in HIV-1 [J].
Ott, David E. .
REVIEWS IN MEDICAL VIROLOGY, 2008, 18 (03) :159-175
[10]   Pan-viral specificity of IFN-induced genes reveals new roles for cGAS in innate immunity [J].
Schoggins, John W. ;
MacDuff, Donna A. ;
Imanaka, Naoko ;
Gainey, Maria D. ;
Shrestha, Bimmi ;
Eitson, Jennifer L. ;
Mar, Katrina B. ;
Richardson, R. Blake ;
Ratushny, Alexander V. ;
Litvak, Vladimir ;
Dabelic, Rea ;
Manicassamy, Balaji ;
Aitchison, John D. ;
Aderem, Alan ;
Elliott, Richard M. ;
Garcia-Sastre, Adolfo ;
Racaniello, Vincent ;
Snijder, Eric J. ;
Yokoyama, Wayne M. ;
Diamond, Michael S. ;
Virgin, Herbert W. ;
Rice, Charles M. .
NATURE, 2014, 505 (7485) :691-+