Applications of nanotechnology for immunology

被引：575

作者：

Smith, Douglas M. ^{[1
,2
]}

Simon, Jakub K. ^{[3
]}

Baker, James R., Jr. ^{[1
,3
]}

机构：

[1] Univ Michigan, Sch Med, Michigan Nanotechnol Inst Med & Biol Sci, Ann Arbor, MI 48109 USA

[2] Univ Michigan, Sch Med, Dept Internal Med, Ann Arbor, MI 48109 USA

[3] NanoBio Corp, Ann Arbor, MI 48105 USA

来源：

NATURE REVIEWS IMMUNOLOGY | 2013年 / 13卷 / 08期

关键词：

VIRUS-LIKE PARTICLES; T-CELL RESPONSES; MUCOSAL IMMUNE-RESPONSES; INFLUENZA-A VIRUS; HEPATITIS-B; DENDRITIC CELLS; ANTIBODY-RESPONSE; CARBON NANOTUBES; IN-VITRO; SURFACTANT NANOEMULSION;

D O I：

10.1038/nri3488

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Nanotechnology uses the unique properties of objects that function as a unit within the overall size range of 1-1,000 nanometres. The engineering of nanostructure materials, including nanoparticles, nanoemulsions or nanotubules, holds great promise for the development of new immunomodulatory agents, as such nanostructures can be used to more effectively manipulate or deliver immunologically active components to target sites. Successful applications of nanotechnology in the field of immunology will enable new generations of vaccines, adjuvants and immunomodulatory drugs that aim to improve clinical outcomes in response to a range of infectious and non-infectious diseases.

引用

页码：592 / 605

页数：14

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