Functionalization via radical cyclization of cyclohexenediol derivatives bound to polystyrene

被引：0

作者：

Berteina, S ^{[1
]}

De Mesmaeker, A ^{[1
]}

Wendeborn, S ^{[1
]}

机构：

[1] Novartis AG, Basel, Switzerland

来源：

SYNLETT | 1999年 / 07期

关键词：

solid phase synthesis; epoxide opening; radical cyclization;

D O I：

暂无

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Radical cyclization reactions involving precursors derived from cyclohexadiene diols were investigated, both, in solution and on the solid phase. A straightforward sequence was established in solution to obtain bicyclic compounds with potential for diversity. Optimized reaction procedures were applied to solid phase synthesis.

引用

页码：1121 / 1123

页数：3

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