Chilling slows anaerobic metabolism to improve anoxia tolerance of insects

被引：12
作者：
Boardman, Leigh [1 ,4 ]
Sorensen, Jesper G. [2 ]
Kostal, Vladimir [3 ]
Simek, Petr [3 ]
Terblanche, John S. [1 ]
机构：
[1] Univ Stellenbosch, Ctr Invas Biol, Dept Conservat Ecol & Entomol, Private Bag X1, ZA-7602 Stellenbosch, South Africa
[2] Aarhus Univ, Sect Genet Ecol & Evolut, Dept Biosci, Ny Munkegade 116, DK-8000 Aarhus C, Denmark
[3] Acad Sci Czech Republic, Inst Entomol, Ctr Biol, Ceske Budejovice, Czech Republic
[4] Univ Florida, Dept Entomol & Nematol, Gainesville, FL 32611 USA
来源：
METABOLOMICS | 2016年 / 12卷 / 12期
基金：
新加坡国家研究基金会;
关键词：
Anoxia; Hypoxia; Cold; Lactic acid; False codling moth; THAUMATOTIBIA-LEUCOTRETA; ALPHA-KETOGLUTARATE; RESPONSES; HYPOXIA; LEPIDOPTERA; MELANOGASTER; TEMPERATURE; TORTRICIDAE;
D O I：
10.1007/s11306-016-1119-1
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
Background Insects are renowned for their ability to survive anoxia. Anoxia tolerance may be enhanced during chilling through metabolic suppression. Aims Here, the metabolomic response of insects to anoxia, both with and without chilling, for different durations (12-36 h) was examined to assess the potential cross-tolerance mechanisms. Results Chilling during anoxia (cold anoxia) significantly improved survival relative to anoxia at warmer temperatures. Reduced intermediate metabolites and increased lactic acid, indicating a switch to anaerobic metabolism, were characteristic of larvae in anoxia. Conclusions Anoxia tolerance was correlated survival improvements after cold anoxia were correlated with a reduction in anaerobic metabolism.
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页数：8
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