ERK1/2 Inhibition Overcomes Resistance to Venetoclax in AML By Altering Drp1-Dependent Mitochondrial Fission and Metabolism

被引：0
|
作者：
Sharma, Priyanka [1 ]
Piya, Sujan [1 ,2 ]
Baran, Natalia [3 ]
Zal, Anna [4 ]
Hindley, Christopher J. [5 ]
Dao, Kim-Hien [6 ]
Sims, Martin [5 ]
Zal, Tomasz [3 ,4 ]
Ruvolo, Vivian [3 ]
Andreeff, Michael [3 ]
Borthakur, Gautam [3 ]
机构：
[1] Univ Texas MD Anderson Canc Ctr, Dept Leukemia, Sect Mol Hematol & Therapy, Houston, TX 77030 USA
[2] Univ Texas MD Anderson Canc Ctr, Div Pathol & Lab Med Clin Trial Operat, Houston, TX 77030 USA
[3] Univ Texas MD Anderson Canc Ctr, Dept Leukemia, Houston, TX 77030 USA
[4] Univ Texas MD Anderson Canc Ctr, Dept Immunol, Houston, TX USA
[5] Astex Pharmaceut, Cambridge, England
[6] Astex Pharmaceut Inc, Pleasanton, CA USA
来源：
BLOOD | 2022年 / 140卷
关键词：
D O I：
10.1182/blood-2022-167171
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
引用
收藏
页码：8789 / 8790
页数：2
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