Genetic relatedness and antimicrobial resistance determinants among clinical isolates of enterococci from Cuba

被引:7
|
作者
Quinones-Perez, D.
Goñi, P.
Rubio, M. C.
Baquero, F.
Gómez-Lus, R.
Del Campo, R.
机构
[1] Hosp Ramon & Cajal, Microbiol Serv, E-28034 Madrid, Spain
[2] Trop Med Inst Pedro Kouri, Dept Bacteriol Mycol, Havana, Cuba
[3] Univ Zaragoza, Fac Med, Dept Microbiol, E-50009 Zaragoza, Spain
[4] Univ Hosp Lozano Blesa, Microbiol Serv, Zaragoza, Spain
关键词
antimicrobial resistance; Cuba; Enterococcus spp; epidemiology; genetic relatedness; resistance;
D O I
10.1111/j.1469-0691.2006.01421.x
中图分类号
R51 [传染病];
学科分类号
100401 ;
摘要
This study describes the genetic relationships and antimicrobial resistance determinants found among 99 clinical isolates of enterococci from 15 different hospitals in Cuba. Pulsed-field gel electrophoresis SmaI analysis demonstrated a high degree of genetic diversity. A limited number of multiresistant Enterococcus faecalis clones, showing resistance to three or more families of antimicrobial agents, were detected simultaneously in different institutions, suggesting inter-hospital circulation of selected clones, and/or selection of particular clones following their introduction into the hospital environment. Antimicrobial resistance determinants, including erm(B), aac(6')-aph(2'), aph(3'), ant(6), vanB (E. faecalis) and vanA (Enterococcus faecium) were detected by PCR in various isolates.
引用
收藏
页码:793 / 797
页数:5
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