Liposarcoma associated with a glass foreign body in a dog

Liposarcoma is an uncommon neoplasm in dogs and is believed to arise de novo and not from malignant transformation of existing lipomas. A causative agent has not been identified. Various types of sarcomas have been associated with foreign bodies, including liposarcomas. Development of foreign body-induced sarcomas depends on the size, surface texture, and physical and chemical properties of the foreign material. Treatment for soft-tissue sarcomas includes early excision with wide surgical borders. Although soft-tissue sarcomas usually are considered resistant to radiation and hyperthermia, these modalities can serve as adjunct treatments to surgical excision.