Influence of disodium EDTA on the nucleation and growth of struvite and carbonate apatite

被引:34
作者
Prywer, Jolanta [1 ]
Olszynski, Marcin [1 ]
机构
[1] Tech Univ Lodz, Inst Phys, PL-93005 Lodz, Poland
关键词
Biocrystallization; Nucleation; Growth from solutions; Biological substances; Phosphates; URINARY STONES; CRYSTALLIZATION; UREASE; RATS;
D O I
10.1016/j.jcrysgro.2013.04.027
中图分类号
O7 [晶体学];
学科分类号
0702 ; 070205 ; 0703 ; 080501 ;
摘要
The effect of disodium EDTA, as an additive, on the crystallization of struvite and carbonate apatite was studied. The growth of struvite crystals and carbonate apatite occurred in the solution of artificial urine at 37 degrees C and at the condition emulating real urinary tract infection. The results demonstrate that the addition of disodium EDTA increases the induction time and decreases the growth efficiency compared to the baseline (without disodium EDTA). The struvite crystal mean and median diameters were found to decrease in the presence of disodium EDTA but the crystal morphology and habit remain almost unchanged. Disodium EDTA has demonstrated its potential to be further investigated in the presence of bacteria and in vivo conditions. (C) 2013 Elsevier B.V. All rights reserved.
引用
收藏
页码:108 / 114
页数:7
相关论文
共 20 条
[1]   GROWTH MORPHOLOGY AND CRYSTAL HABIT OF STRUVITE CRYSTALS (MGNH4PO4.6H2O) [J].
ABBONA, F ;
BOISTELLE, R .
JOURNAL OF CRYSTAL GROWTH, 1979, 46 (03) :339-354
[2]   Infrared analysis of urinary stones, using a single reflection accessory and a KBr pellet transmission [J].
Benramdane, L. ;
Bouatia, M. ;
Idrissi, M. O. B. ;
Draoui, M. .
SPECTROSCOPY LETTERS, 2008, 41 (02) :72-80
[3]   Urinary infection stones [J].
Bichler, KH ;
Eipper, E ;
Naber, K ;
Braun, V ;
Zimmermann, R ;
Lahme, S .
INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS, 2002, 19 (06) :488-498
[4]   Developmental toxicity of metal chelating agents [J].
Domingo, JL .
REPRODUCTIVE TOXICOLOGY, 1998, 12 (05) :499-510
[5]   Urothelial carcinogenesis in the urinary bladder of male rats treated with muraglitazar, a PPAR α/γ agonist:: Evidence for urolithiasis as the inciting event in the mode of action [J].
Dominick, Mark A. ;
White, Melvin R. ;
Sanderson, Thomas P. ;
Van Vleet, Terry ;
Cohen, Samuel M. ;
Arnold, Lora E. ;
Cano, Marty ;
Tannehill-Gregg, Sarah ;
Moehlenkamp, Jeffrey D. ;
Waites, Crystal R. ;
Schilling, Beth E. .
TOXICOLOGIC PATHOLOGY, 2006, 34 (07) :903-920
[6]  
Final Report on the Safety Assessment of EDTA, 2002, INT J TOXICOL, V21, P95
[7]  
GRIFFITH DP, 1976, INVEST UROL, V13, P346
[8]   Kinetics of crystallization preceded by metastable-phase formation [J].
Kashchiev, D ;
Sato, K .
JOURNAL OF CHEMICAL PHYSICS, 1998, 109 (19) :8530-8540
[9]  
Kashchiev D., 2000, Nucleation: Basic Theory with Applications
[10]   THE ECOLOGY AND PATHOGENICITY OF UREASE-PRODUCING BACTERIA IN THE URINARY-TRACT [J].
MCLEAN, RJC ;
NICKEL, JC ;
CHENG, KJ ;
COSTERTON, JW .
CRC CRITICAL REVIEWS IN MICROBIOLOGY, 1988, 16 (01) :37-79