CDK inhibitor targets: a hit or miss proposition? Cyclin-dependent kinase inhibitors kill tumor cells by downregulation of anti-apoptotic proteins

被引:4
作者
Dai, Y
Grant, S
机构
[1] Virginia Commonwealth Univ, Massey Canc Ctr, Div Hematol Oncol, Richmond, VA USA
[2] Virginia Commonwealth Univ, Massey Canc Ctr, Dept Med, Richmond, VA USA
[3] Virginia Commonwealth Univ, Massey Canc Ctr, Dept Biochem & Pharmacol, Richmond, VA USA
关键词
cyclin-dependent kinases; CDK inhibitors; anti-apoptotic proteins; transcriptional regulation; apoptosis;
D O I
10.4161/cbt.5.2.2568
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
引用
收藏
页码:171 / 173
页数:3
相关论文
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