Existing and future vaccines against brucellosis in small ruminants

被引:16
作者
Blasco, JM [1 ]
机构
[1] CITA, Anim Hlth Unit, Zaragoza 50080, Spain
关键词
sheep; abortion; brucellosis; goat; vaccination; control;
D O I
10.1016/j.smallrumres.2005.07.034
中图分类号
S8 [畜牧、 动物医学、狩猎、蚕、蜂];
学科分类号
0905 ;
摘要
Conjunctival vaccination with Rev-1 is the best method available for controlling Brucella melitensis infection. The rough RB51 and VRTM1 strains do not interfere with diagnosis, but are ineffective in sheep or goats. Recombinant vaccine strains deleted in genes for relevant proteins associated to diagnostic tests are, for the moment, ineffective. DNA-based vaccines are not available. Inactivated vaccines in new generation adjuvants are being also investigated. (c) 2005 Elsevier B.V. All rights reserved.
引用
收藏
页码:33 / 37
页数:5
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