An Efficient Access to Aspermytin A and Oblongolide C through an Intramolecular Nitrile Oxide-Alkene [3+2] Cycloaddition

被引：6

作者：

Inoue, Atsushi ^{[1
]}

Kanematsu, Makoto ^{[1
]}

Mori, Seiji ^{[2
]}

Yoshida, Masahiro ^{[1
]}

Shishido, Kozo ^{[1
]}

机构：

[1] Univ Tokushima, Grad Sch Pharmaceut Sci, Tokushima 7708505, Japan

[2] Ibaraki Univ, Fac Sci, Dept Chem, Bunkyo Ku, Mito, Ibaraki 3108512, Japan

来源：

SYNLETT | 2013年 / 24卷 / 01期

关键词：

total synthesis; enantioselectivity; cycloaddition; aspermytin A; nitrile oxide; ENANTIOSELECTIVE SYNTHESIS; 1,3-DIPOLAR CYCLOADDITION; ENE REACTIONS; (+)-ALBICANOL; EQUIVALENT; FUNGUS; ROUTE; IBX;

D O I：

10.1055/s-0032-1317693

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The second generation synthesis of (+)-aspermytin A and the first total synthesis of (-)-oblongolide C have been accomplished employing an intramolecular nitrile oxide-alkene [3+2] cycloaddition as the key step.

引用

页码：61 / 64

页数：4

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