Pure Protein Scaffolds from Pickering High Internal Phase Emulsion Template

被引：120
|
作者：
Li, Zifu [1 ]
Xiao, Manda [2 ]
Wang, Jianfang [2 ]
Ngai, To [1 ]
机构：
[1] Chinese Univ Hong Kong, Dept Chem, Shatin, Hong Kong, Peoples R China
[2] Chinese Univ Hong Kong, Dept Phys, Shatin, Hong Kong, Peoples R China
来源：
MACROMOLECULAR RAPID COMMUNICATIONS | 2013年 / 34卷 / 02期
关键词：
Pickering HIPE templates; porous materials; pure protein scaffolds; SILICA; FOAMS;
D O I：
10.1002/marc.201200553
中图分类号：
O63 [高分子化学（高聚物）];
学科分类号：
070305 ; 080501 ; 081704 ;
摘要：
The formation of hierarchical porous protein scaffolds from oil-in-water (o/w) high internal phase emulsions (HIPEs) stabilized by bovine serum albumin (BSA) protein nanoparticles (Pickering HIPE) is reported. The route consists of three principal steps. First, a stable o/w HIPE stabilized by BSA protein nanoparticles is formulated. Next, crosslinking the dispersed protein nanoparticles gives rise to a gel in the continuous water phase to freeze the emulsion's microstructure. Finally, removal of the oil components and water directly leads to a three dimensional, bimodal meso-macroporous protein scaffold, which is suitable for a wide range of biomedical applications.
引用
收藏
页码：169 / 174
页数：6
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