Retinal Pigment Epithelial Detachment in Age-Related Macular Degeneration

被引:25
作者
Karampelas, Michael [1 ]
Malamos, Panagiotis [2 ]
Petrou, Petros [3 ]
Georgalas, Ilias [3 ]
Papaconstantinou, Dimitrios [3 ]
Brouzas, Dimitrios [3 ]
机构
[1] Hippokrateion Hosp, Dept Ophthalmol, Athens, Greece
[2] Imaging Fundus & Macula, Athens, Greece
[3] Natl & Kapodistrian Univ Athens, Div Ophthalmol 1, Sch Med, G Gennimatas Gen Hosp, Athens, Greece
关键词
Age-related macular degeneration; Drusenoid; Fibrovascular; Haemorrhagic; Pigment epithelial detachment; Serous; OPTICAL COHERENCE TOMOGRAPHY; OCCULT CHOROIDAL NEOVASCULARIZATION; ANTI-VEGF THERAPY; BRUCHS MEMBRANE; NATURAL-HISTORY; INTRAVITREAL BEVACIZUMAB; MORPHOMETRIC-ANALYSIS; PHOTODYNAMIC THERAPY; SEROUS DETACHMENTS; VISUAL-ACUITY;
D O I
10.1007/s40123-020-00291-5
中图分类号
R77 [眼科学];
学科分类号
100212 ;
摘要
Retinal pigment epithelial detachment is defined as a separation of the retinal pigment epithelium from the inner collagenous layer of Bruch's membrane. It is a common manifestation in both dry and wet types of age-related macular degeneration. This review aims to provide a comprehensive guide to the pathophysiology, clinical and imaging characteristics, natural course and treatment of the various types of pigment epithelial detachments in order to assist in diagnosis and management of this important feature of age-related macular degeneration.
引用
收藏
页码:739 / 756
页数:18
相关论文
共 85 条
[1]   INTRAVITREAL BEVACIZUMAB IN VASCULAR PIGMENT EPITHELIUM DETACHMENT AS A RESULT OF SUBFOVEAL OCCULT CHOROIDAL NEOVASCULARIZATION IN AGE-RELATED MACULAR DEGENERATION [J].
Ach, Thomas ;
Hoeh, Alexandra E. ;
Ruppenstein, Mira ;
Kretz, Florian T. A. ;
Dithmar, Stefan .
RETINA-THE JOURNAL OF RETINAL AND VITREOUS DISEASES, 2010, 30 (09) :1420-1425
[2]   Indocyanine green angiography of drusen [J].
Arnold, JJ ;
Quaranta, M ;
Soubrane, G ;
Sarks, SH ;
Coscas, G .
AMERICAN JOURNAL OF OPHTHALMOLOGY, 1997, 124 (03) :344-356
[3]   Comparison of anti-VEGF therapies on fibrovascular pigment epithelial detachments in age-related macular degeneration [J].
Au, Adrian ;
Parikh, Vishal S. ;
Singh, Rishi P. ;
Ehlers, Justis P. ;
Yuan, Alex ;
Rachitskaya, Aleksandra V. ;
Sears, Jonathan E. ;
Srivastava, Sunil K. ;
Kaiser, Peter K. ;
Schachat, Andrew P. ;
Martin, Daniel F. ;
Modi, Yasha .
BRITISH JOURNAL OF OPHTHALMOLOGY, 2017, 101 (07) :970-975
[4]   QUANTITATIVE ANALYSIS OF PIGMENT EPITHELIAL DETACHMENT RESPONSE TO DIFFERENT ANTI-VASCULAR ENDOTHELIAL GROWTH FACTOR AGENTS IN WET AGE-RELATED MACULAR DEGENERATION [J].
Balaskas, Konstantinos ;
Karampelas, Michael ;
Horani, Mania ;
Hotu, Oana ;
Keane, Pearse ;
Aslam, Tariq .
RETINA-THE JOURNAL OF RETINAL AND VITREOUS DISEASES, 2017, 37 (07) :1297-1304
[5]   Autofluorescence Patterns as a Predictive Factor for Neovascularization [J].
Batioglu, Figen ;
Demirel, Sibel ;
Ozmert, Emin ;
Oguz, Yesim Gedik ;
Ozyol, Pelin .
OPTOMETRY AND VISION SCIENCE, 2014, 91 (08) :950-955
[6]  
BIRD AC, 1991, EYE, V5, P1
[7]  
BIRD AC, 1986, T OPHTHAL SOC UK, V105, P674
[8]   SEROUS DETACHMENTS OF THE RETINAL-PIGMENT EPITHELIUM IN PATIENTS WITH SENILE MACULAR DISEASE [J].
BRAUNSTEIN, RA ;
GASS, JDM .
AMERICAN JOURNAL OF OPHTHALMOLOGY, 1979, 88 (04) :652-660
[9]   CLINICOPATHOLOGICAL CORRELATION OF DRUSEN AND RETINAL-PIGMENT EPITHELIAL ABNORMALITIES IN AGE-RELATED MACULAR DEGENERATION [J].
BRESSLER, NM ;
SILVA, JC ;
BRESSLER, SB ;
FINE, SL ;
GREEN, WR .
RETINA-THE JOURNAL OF RETINAL AND VITREOUS DISEASES, 1994, 14 (02) :130-142
[10]   Significance of the hyperautofluorescent ring associated with choroidal neovascularisation in eyes undergoing anti-VEGF therapy for wet age-related macular degeneration [J].
Camacho, Natalia ;
Barteselli, Giulio ;
Nezgoda, Joseph T. ;
El-Emam, Sharif ;
Cheng, Lingyun ;
Bartsch, Dirk-Uwe ;
Freeman, William R. .
BRITISH JOURNAL OF OPHTHALMOLOGY, 2015, 99 (09) :1277-1283