One-pot synthesis of 2,4,5-trisubstituted 1,2,3-triazoles through the cascade reactions of acid chlorides, terminal acetylenes, sodium azide and aryl halides

被引：11
作者：
Liu, Xiang [1 ,2 ]
Li, Jihui [1 ,2 ]
Chen, Baohua [1 ,2 ]
机构：
[1] Lanzhou Univ, State Key Lab Appl Organ Chem, Lanzhou 730000, Gansu, Peoples R China
[2] Key Lab Nonferrous Met Chem & Resources Utilizat, Lanzhou 730000, Peoples R China
来源：
NEW JOURNAL OF CHEMISTRY | 2013年 / 37卷 / 04期
基金：
美国国家科学基金会;
关键词：
REGIOSELECTIVE SYNTHESIS; CLICK-CHEMISTRY; 1,4,5-TRISUBSTITUTED 1,2,3-TRIAZOLES; ALKYNE CYCLOADDITION; EFFICIENT SYNTHESIS; DERIVATIVES; CATALYSIS; 1,2,3-NH-TRIAZOLES; LIGATION; ALCOHOLS;
D O I：
10.1039/c3nj40912k
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
An efficient one-pot reaction of acid chlorides, terminal acetylenes, sodium azide and aryl halides is developed for the regioselective synthesis of 2,4,5-trisubstituted 1,2,3-triazoles. The method is general, convenient, eco-friendly, atom-economical, and could provide excellent yields and regioselectivities.
引用
收藏
页码：965 / 968
页数：4
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