Fatal human eosinophilic meningo-encephalitis caused by CNS co-infection with Halicephalobus gingivalis and West Nile virus

被引：6
作者：
Anwar, M. A. [1 ]
Gokozan, H. N. [2 ]
Ball, M. K. [2 ]
Otero, J. [2 ]
McGwire, B. S. [1 ]
机构：
[1] Ohio State Univ, Dept Internal Med, Div Infect Dis, Columbus, OH 43210 USA
[2] Ohio State Univ, Dept Pathol, Wexner Med Ctr, Columbus, OH 43210 USA
来源：
PARASITOLOGY INTERNATIONAL | 2015年 / 64卷 / 05期
关键词：
Halicephalobus; Eosinophilic encephalitis; Granuloma; West Nile virus; JAPANESE ENCEPHALITIS-VIRUS; INFECTION; DELETRIX; MICRONEMA; DISEASE; HORSE; MICE;
D O I：
10.1016/j.parint.2015.06.001
中图分类号：
R38 [医学寄生虫学]; Q [生物科学];
学科分类号：
07 ; 0710 ; 09 ; 100103 ;
摘要：
The saprophytic nematode Halicephalobus is a rare cause of fatal human meningo-encephalitis, and West Nile virus is neurotropic flavivirus implicated in a variety of clinical neurologic syndromes. Here we report a case of rapidly progressive CNS encephalopathy and death. Serologic, immuno-histochemical, histopathologic and nucleic acid studies demonstrate the presence of active Halicephalobus and West Nile virus in the CNS tissue. This is the first reported case of co-infection with these neurotropic pathogens. (C) 2015 Published by Elsevier Ireland Ltd.
引用
收藏
页码：417 / 420
页数：4
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