Fatal human eosinophilic meningo-encephalitis caused by CNS co-infection with Halicephalobus gingivalis and West Nile virus

被引：7

作者：

Anwar, M. A. ^{[1
]}

Gokozan, H. N. ^{[2
]}

Ball, M. K. ^{[2
]}

Otero, J. ^{[2
]}

McGwire, B. S. ^{[1
]}

机构：

[1] Ohio State Univ, Dept Internal Med, Div Infect Dis, Columbus, OH 43210 USA

[2] Ohio State Univ, Dept Pathol, Wexner Med Ctr, Columbus, OH 43210 USA

来源：

PARASITOLOGY INTERNATIONAL | 2015年 / 64卷 / 05期

关键词：

Halicephalobus; Eosinophilic encephalitis; Granuloma; West Nile virus; JAPANESE ENCEPHALITIS-VIRUS; INFECTION; DELETRIX; MICRONEMA; DISEASE; HORSE; MICE;

D O I：

10.1016/j.parint.2015.06.001

中图分类号：

R38 [医学寄生虫学]; Q [生物科学];

学科分类号：

07 ; 0710 ; 09 ; 100103 ;

摘要：

The saprophytic nematode Halicephalobus is a rare cause of fatal human meningo-encephalitis, and West Nile virus is neurotropic flavivirus implicated in a variety of clinical neurologic syndromes. Here we report a case of rapidly progressive CNS encephalopathy and death. Serologic, immuno-histochemical, histopathologic and nucleic acid studies demonstrate the presence of active Halicephalobus and West Nile virus in the CNS tissue. This is the first reported case of co-infection with these neurotropic pathogens. (C) 2015 Published by Elsevier Ireland Ltd.

引用

页码：417 / 420

页数：4

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