Mechanical Circulatory Support Devices and Transcatheter Aortic Valve Implantation (from the National Inpatient Sample)

被引:36
作者
Singh, Vikas [1 ]
Patel, Samir V. [2 ]
Savani, Chirag [3 ]
Patel, Nileshkumar J. [1 ]
Patel, Nilay [4 ]
Arora, Shilpkumar [5 ]
Panaich, Sidakpal S. [6 ]
Deshmukh, Abhishek [7 ]
Cleman, Michael [8 ]
Mangi, Abeel [9 ]
Forrest, John K. [9 ]
Badheka, Apurva O. [9 ]
机构
[1] Univ Miami, Miller Sch Med, Dept Cardiol, Miami, FL 33136 USA
[2] Western Reserve Hlth Educ, Internal Med Dept, Youngstown, OH USA
[3] New York Med Coll, Dept Publ Hlth, Valhalla, NY 10595 USA
[4] St Peters Univ Hosp, Internal Med Dept, New Brunswick, NJ USA
[5] Mt Sinai St Lukes Roosevelt Hosp, Dept Internal Med, New York, NY USA
[6] Detroit Med Ctr, Cardiol Dept, Detroit, MI USA
[7] Mayo Clin, Cardiol Dept, Rochester, MN USA
[8] Yale Univ, Sch Med, Cardiol Dept, New Haven, CT USA
[9] Everett Clin, Intervent Cardiol Dept, Everett, WA 98201 USA
关键词
PERCUTANEOUS CORONARY INTERVENTION; UNITED-STATES; ATRIAL-FIBRILLATION; EMERGENT USE; REPLACEMENT; OUTCOMES; COMPLICATIONS; EXPERIENCE; HOSPITALIZATION; STENOSIS;
D O I
10.1016/j.amjcard.2015.08.020
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
High-risk surgical patients undergoing transcatheter aortic valve implantation (TAVI) represent an emerging population, which may benefit from short-term use of mechanical circulatory support (MCS) devices. The aim of this study was to determine the practice and inhospital outcomes of MCS utilization in patients undergoing TAVI. We analyzed data from Nationwide Inpatient Sample (2011 and 2012) using the International Classification of Diseases, Ninth Revision, Clinical Modification procedure codes. A total of 1,794 TAVI procedures (375 hospitals in the United States) were identified of which 190 (10.6%) used an MCS device (MCS group) and 1,604 (89.4%) did not (non-MCS group). The use of MCS devices with TAVI was associated with significant increase in the inhospital mortality (14.9% vs 3.5%, p <0.01). The mean length (11.8 +/- 0.8 vs 8.1 +/- 0.2 days, p <0.01) and cost ($68,997 +/- 3,656 vs $55,878 +/- 653, p = 0.03) of hospitalization were also significantly greater in the MCS group. Ventricular fibrillation arrest, transapical access for TAVI, and cardiogenic shock were the most significant predictors of MCS use during TAVI. In the multivariate model, use of any MCS device was found to be an independent predictor of increased mortality (odds ratio 3.5, 95% confidence interval 2.6 to 4.6, p <0.0001) and complications (odds ratio 3.3, 95% confidence interval 2.8 to 3.9, p <0.0001). The propensity score matched analysis also showed a similar result. In conclusion, the unacceptably high rates of mortality and complications coupled with a significant increase in the length and cost of hospitalization should raise concerns about utility of MCS devices during TAVI in this prohibitive surgical risk population. (C) 2015 Elsevier Inc. All rights reserved.
引用
收藏
页码:1574 / 1580
页数:7
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