Robust synthesis of F-BODIPYs

被引：15

作者：

Beh, Michael Helmut Reynolds ^{[1
]}

Douglas, Katherine Isabelle Biehn ^{[1
]}

House, Kelsey Taylor Elver ^{[1
]}

Murphy, Alexandra Celeste ^{[1
]}

Sinclair, Jackson Scott Testemale ^{[1
]}

Thompson, Alison ^{[1
]}

机构：

[1] Dalhousie Univ, Dept Chem, POB 15000, Halifax, NS B3H 4R2, Canada

来源：

ORGANIC & BIOMOLECULAR CHEMISTRY | 2016年 / 14卷 / 48期

基金：

加拿大自然科学与工程研究理事会;

关键词：

DIPYRRINS; BORON; DYES; SUBSTITUTION; DERIVATIVES; CHEMISTRY; DESIGN;

D O I：

10.1039/c6ob02238c

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A protocol is established for the high-yielding synthesis of F-BODIPYs involving non-anhydrous reagents and not requiring precautions to exclude moisture. This simple and robust strategy simply requires a second addition of NEt3 and BF3 center dot OEt2, midway through the reaction period. The ratio and amounts of NEt3 and BF3 center dot OEt2 used in each aliquot are critical to success (6 : 9 for each aliquot). The protocol can be completed using bench-dry apparatus, without need to achieve and maintain anhydrous conditions or solvents.

引用

页码：11473 / 11479

页数：7

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