In Vitro Activities of Eight Antifungal Drugs against 106 Waterborne and Cutaneous Exophiala Species

被引：12

作者：

Najafzadeh, M. J. ^{[1
,2
]}

Keisari, M. Saradeghi ^{[2
]}

Vicente, V. A. ^{[2
,3
]}

Feng, P. ^{[4
]}

Shamsian, S. A. A. ^{[1
]}

Rezaei-Matehkolaei, A. ^{[5
]}

de Hoog, G. S. ^{[2
,3
,6
,7
,8
,9
]}

Curfs-Breuker, I. ^{[10
]}

Meis, J. F. ^{[10
,11
]}

机构：

[1] Mashhad Univ Med Sci, Sch Med, Ghaem Hosp, Dept Parasitol & Mycol, Mashhad, Iran

[2] CBS KNAW Fungal Biodivers Ctr, Utrecht, Netherlands

[3] Univ Fed Parana, Dept Basic Pathol, BR-80060000 Curitiba, Parana, Brazil

[4] Sun Yat Sen Univ, Affiliated Hosp 3, Guangzhou 510275, Guangdong, Peoples R China

[5] Ahvaz Jundishapur Univ Med Sci, Sch Med, Dept Med Mycol, Ahvaz, Iran

[6] Univ Amsterdam, Inst Biodivers & Ecosyst Dynam, Amsterdam, Netherlands

[7] Sun Yat Sen Univ, Guangzhou 510275, Guangdong, Peoples R China

[8] Peking Univ, Hlth Sci Ctr, Res Ctr Med Mycol, Beijing 100871, Peoples R China

[9] King Abdulassiz Univ, Jeddah, Saudi Arabia

[10] Canisius Wilhelmina Hosp, Dept Med Microbiol & Infect Dis, Nijmegen, Netherlands

[11] Radboud Univ Nijmegen, Med Ctr, Dept Med Microbiol, Nijmegen, Netherlands

来源：

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY | 2013年 / 57卷 / 12期

关键词：

SUSCEPTIBILITY; PHEOHYPHOMYCOSIS; IDENTIFICATION; DERMATITIDIS; DISEASE; AGENT; FUNGI;

D O I：

10.1128/AAC.01629-13

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

The in vitro activities of eight antifungal drugs against 106 clinical and environmental isolates of waterborne and cutaneous Exophiala species were tested. The MICs and minimum effective concentrations for 90% of the strains tested (n = 106) were, in increasing order, as follows: posaconazole, 0.063 mu g/ml; itraconazole, 0.25 mu g/ml; micafungin, 1 mu g/ml; voriconazole, 2 mu g/ml; isavuconazole, 4 mu g/ml; caspofungin, 8 mu g/ml; amphotericin B, 16 mu g/ml; fluconazole, 64 mu g/ml.

引用

页码：6395 / 6398

页数：4

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