Isoflavanones from the Stem of Cassia siamea and Their Anti-tobacco Mosaic Virus Activities

被引：35

作者：

Hu, Qiu-Fen ^{[1
,2
]}

Niu, De-Yun ^{[1
,2
,3
]}

Zhou, Bin ^{[1
,2
]}

Ye, Yan-Qing ^{[1
,2
]}

Du, Gang ^{[1
,2
]}

Meng, Chun-Yang ^{[1
,2
]}

Gao, Xue-Mei ^{[1
,2
]}

机构：

[1] Yunnan Univ Nationalities, Key Lab Chem Ethn Med Resources, State Ethn Affairs Commiss, Kunming 650031, Peoples R China

[2] Yunnan Univ Nationalities, Minist Educ, Kunming 650031, Peoples R China

[3] Yunnan Acad Tobacco Sci, Key Lab Tobacco Chem Yunnan Prov, Kunming 650106, Yunnan, Peoples R China

来源：

BULLETIN OF THE KOREAN CHEMICAL SOCIETY | 2013年 / 34卷 / 10期

基金：

中国国家自然科学基金;

关键词：

Cassia siamea; Isoflavanones; Anti-tobacco mosaic virus activity; FISTULA; ROOT;

D O I：

10.5012/bkcs.2013.34.10.3013

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Two new isoflavanones, (3R) 7,2',4'-trihydroxy-3'-methoxy-5-methoxycarbonyl-isoflavanone (1) and (3R) 7,2'-dihydroxy-3',4'-dimethoxy-5-methoxycarbonyl-isoflavanone (2), together with six known isoflavanones (3-8), were isolated from the stems of Cassia siamea. The structure of 1-8 was elucidated by spectroscopic methods including extensive 1D- and 2D-NMR techniques. Compounds 1, 2, 5-8 were evaluated for their anti-tobacco mosaic virus (Anti-TMV) activity. The results showed that compounds 1 and 6 showed potential anti-TMV activity with inhibition rates of 24.6% and 26.9%, respectively. Compounds 2, 5, 7, 8 also showed anti-TMV activity with inhibition rates in the range of 11.8-18.6%.

引用

页码：3013 / 3016

页数：4

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