Hypertension in adult polycystic kidney disease: a narrative review

被引：0

作者：

Mian, Sarah ^{[1
]}

Acharya, Yogesh ^{[1
]}

Dahal, Ranjan ^{[2
]}

机构：

[1] Avalon Univ, Sch Med, Curacao, Neth Antilles

[2] St Peters Univ Hosp, New Brunswick, NJ 08901 USA

来源：

JOURNAL OF RENAL INJURY PREVENTION | 2019年 / 8卷 / 02期

关键词：

Adult polycystic kidney disease; Hypertension; Antihypertensive agents; Prevention and control; Renin-angiotensin-aldosterone system; End stage renal disease; Glomerular filtration rate; Chronic kidney disease; CONVERTING-ENZYME-INHIBITORS; BLOOD-PRESSURE; ENDOTHELIN; PROGRESSION; ADPKD;

D O I：

10.15171/jrip.2019.23

中图分类号：

R5 [内科学]; R69 [泌尿科学（泌尿生殖系疾病）];

学科分类号：

1002 ; 100201 ;

摘要：

Autosomal dominant polycystic kidney disease (ADPKD) is an inherited renal disorder that impacts approximately 12 million worldwide. It is characterized by bilateral kidney enlargement and cystic growth. Hypertension (HTN) is a focal point in the management of ADPKD and is linked to a faster progression to end stage renal disease. Current novel therapies have proven to reduce the progression of renal damage. The ideal goal is to minimize risk through preventative studies and pharmacology to further increase life expectancy and quality. The purpose of this article is to highlight the importance of blood pressure management in ADPKD and review current literature to determine the most effective preventative pharmacotherapy.

引用

页码：122 / 126

页数：5

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