Pregnancy in Chronic Kidney Disease: questions and answers in a changing panorama

被引：33

作者：

Piccoli, Giorgina Barbara ^{[1
]}

Cabiddu, Gianfranca ^{[2
]}

Attini, Rossella ^{[3
]}

Vigotti, Federica ^{[1
]}

Fassio, Federica ^{[3
]}

Rolfo, Alessandro ^{[3
]}

Giuffrida, Domenica ^{[3
]}

Pani, Antonello ^{[2
]}

Gaglioti, Piero ^{[3
]}

Todros, Tullia ^{[3
]}

机构：

[1] Univ Turin, Dept Clin & Biol Sci, SS Nefrol, ASOU San Luigi Gonzaga, Turin, Italy

[2] Brotzu Hosp, SCDU Nephrol, Cagliari, Italy

[3] Univ Turin, ASOU OIRM S Anna, Dept Obstet, Materno Foetal Unit, Turin, Italy

来源：

BEST PRACTICE & RESEARCH CLINICAL OBSTETRICS & GYNAECOLOGY | 2015年 / 29卷 / 05期

关键词：

pregnancy; chronic kidney disease (CKD); proteinuria; hypertension; glomerulonephritis and interstitial nephropathies; dialysis and transplantation; GLOMERULAR-FILTRATION-RATE; SYSTEMIC-LUPUS-ERYTHEMATOSUS; STAGE RENAL-DISEASE; IMMUNOSUPPRESSIVE DRUGS; MYCOPHENOLATE-MOFETIL; TRANSPLANT RECIPIENTS; VESICOURETERAL REFLUX; NEONATAL OUTCOMES; CKD PATIENTS; WOMEN;

D O I：

10.1016/j.bpobgyn.2015.02.005

中图分类号：

R71 [妇产科学];

学科分类号：

100211 ;

摘要：

Chronic kidney disease (CKD) is increasingly encountered in pregnancy because of greater diagnostic awareness, which is a reflection of the newer, broader definitions (i.e., any changes in blood or urine composition or at imaging, or a glomerular filtration rate (GFR) of <60 mL/min lasting at least 3 months) and of increased incidence (higher maternal age and better outcomes of several kidney diseases). CKD is extremely heterogeneous and may be described by the degree of GFR reduction (CKD stages), the presence of proteinuria and hypertension and the type of kidney disease; the risk of adverse pregnancy-related events increases as GFR decreases and it is affected by proteinuria and hypertension. Specific risks are reported in various diseases such as lupus nephropathy or diabetic nephropathy. While transplantation at least partially restores fertility in end-stage kidney disease, pregnancy on dialysis is increasingly reported. This chapter deals with the available evidence on the management of CKD patients in pregnancy. (C) 2015 Elsevier Ltd. All rights reserved.

引用

页码：625 / 642

页数：18

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