Remote meta C-H bond functionalization of 2-phenethylsulphonic acid and 3-phenylpropanoic acid derivatives

被引：53

作者：

Modak, Atanu ^{[1
]}

Mondal, Anirban ^{[1
]}

Watile, Rahul ^{[1
]}

Mukherjee, Semanti ^{[1
]}

Maiti, Debabrata ^{[1
]}

机构：

[1] Indian Inst Technol, Dept Chem, Bombay 400076, Maharashtra, India

来源：

CHEMICAL COMMUNICATIONS | 2016年 / 52卷 / 96期

关键词：

ELECTRON-DEFICIENT ARENES; DIRECTING GROUP; CONJUGATED POLYMERS; ACTIVATION; OLEFINATION; ARYLATION; TEMPLATE; BORYLATION; LIGAND; SELECTIVITY;

D O I：

10.1039/c6cc08302a

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

This discovery illustrates selective meta C-H bond activation from multiple non-equivalent C-H bonds present in medicinally relevant arylethanesulfonic acid and the 2-arylpropanoic acid moiety using weakly coordinating nitrile as a directing group. Transformation of the meta olefinated compounds to important organic molecules has been demonstrated. Efforts were made to obtain mechanistic detail of the meta C-H bond functionalization reaction.

引用

页码：13916 / 13919

页数：4

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