Remote meta C-H bond functionalization of 2-phenethylsulphonic acid and 3-phenylpropanoic acid derivatives

被引：53
作者：
Modak, Atanu [1 ]
Mondal, Anirban [1 ]
Watile, Rahul [1 ]
Mukherjee, Semanti [1 ]
Maiti, Debabrata [1 ]
机构：
[1] Indian Inst Technol, Dept Chem, Bombay 400076, Maharashtra, India
来源：
CHEMICAL COMMUNICATIONS | 2016年 / 52卷 / 96期
关键词：
ELECTRON-DEFICIENT ARENES; DIRECTING GROUP; CONJUGATED POLYMERS; ACTIVATION; OLEFINATION; ARYLATION; TEMPLATE; BORYLATION; LIGAND; SELECTIVITY;
D O I：
10.1039/c6cc08302a
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
This discovery illustrates selective meta C-H bond activation from multiple non-equivalent C-H bonds present in medicinally relevant arylethanesulfonic acid and the 2-arylpropanoic acid moiety using weakly coordinating nitrile as a directing group. Transformation of the meta olefinated compounds to important organic molecules has been demonstrated. Efforts were made to obtain mechanistic detail of the meta C-H bond functionalization reaction.
引用
收藏
页码：13916 / 13919
页数：4
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