Update on Diffuse Alveolar Hemorrhage and Pulmonary Vasculitis

被引：68
作者：
Krause, Megan L.
Cartin-Ceba, Rodrigo [1 ]
Specks, Ulrich [1 ]
Peikert, Tobias [1 ,2 ]
机构：
[1] Mayo Clin, Div Pulm & Crit Care, Dept Internal Med, Rochester, MN 55905 USA
[2] Mayo Clin, Dept Immunol, Rochester, MN 55905 USA
来源：
IMMUNOLOGY AND ALLERGY CLINICS OF NORTH AMERICA | 2012年 / 32卷 / 04期
关键词：
Pulmonary vasculitis; Diffuse alveolar hemorrhage; ANCA-associated vasculitis; Granulomatosis with polyangiitis; Microscopic polyangiitis; Eosinophilic granulomatosis with polyangiitis; ANTIBODY-ASSOCIATED VASCULITIS; ANCA-ASSOCIATED VASCULITIS; STEM-CELL TRANSPLANT; DAILY ORAL CYCLOPHOSPHAMIDE; RECOMBINANT FACTOR VIIA; SMALL-VESSEL VASCULITIS; CHURG-STRAUSS-SYNDROME; OPEN LUNG BIOPSIES; TERM-FOLLOW-UP; WEGENERS-GRANULOMATOSIS;
D O I：
10.1016/j.iac.2012.08.001
中图分类号：
R392 [医学免疫学];
学科分类号：
100102 ;
摘要：
Diffuse alveolar hemorrhage is a clinical syndrome that can be a manifestation of multiple different causes. Identification of the underlying etiology is of utmost importance and dictates treatment. Pulmonary vasculitis including antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV) is a common cause of diffuse alveolar hemorrhage. For MV, treatment includes induction followed by maintenance therapy. Rituximab has an increasing role in the treatment of AAV.
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页码：587 / +
页数：15
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