The Treg/Th17 cell ratio is reduced in the skin lesions of patients with pyoderma gangrenosum

被引：64

作者：

Caproni, M. ^{[1
]}

Antiga, E. ^{[1
]}

Volpi, W. ^{[1
]}

Verdelli, A. ^{[1
]}

Venegoni, L. ^{[2
]}

Quaglino, P. ^{[3
]}

Fabbri, P. ^{[1
]}

Marzano, A. V. ^{[2
]}

机构：

[1] Univ Florence, Dept Surg & Translat Med, Dermatol Sect, I-50125 Florence, Italy

[2] Univ Milan, Dipartimento Fisiopatol Med Chirurg & Trapianti, Unita Operat Dermatol, Osped Maggiore Policlin,IRCCS Fdn Ca Granda, Milan, Italy

[3] Univ Turin, Dept Biomed Sci & Human Oncol, Dermatol Clin 1, I-10124 Turin, Italy

来源：

BRITISH JOURNAL OF DERMATOLOGY | 2015年 / 173卷 / 01期

关键词：

REGULATORY T-CELLS; MATRIX METALLOPROTEINASES; ATOPIC-DERMATITIS; SWEETS-SYNDROME; DISEASES; CYTOKINES; USTEKINUMAB; TACROLIMUS; EXPRESSION;

D O I：

10.1111/bjd.13670

中图分类号：

R75 [皮肤病学与性病学];

学科分类号：

100206 ;

摘要：

引用

页码：275 / 278

页数：4

共 15 条

[1]

Agarwal S, 2008, J RHEUMATOL, V35, P515

[2] Regulatory T cells in the skin lesions and blood of patients with systemic sclerosis and morphoea [J].

Antiga, E. ;

Quaglino, P. ;

Bellandi, S. ;

Volpi, W. ;

Del Bianco, E. ;

Comessatti, A. ;

Osella-Abate, S. ;

De Simone, C. ;

Marzano, A. ;

Bernengo, M. G. ;

Fabbri, P. ;

Caproni, M. .

BRITISH JOURNAL OF DERMATOLOGY, 2010, 162 (05) :1056-1063

[3] Mechanisms of impaired regulation by CD4+CD25+FOXP3+ regulatory T cells in human autoimmune diseases [J].

Buckner, Jane Hoyt .

NATURE REVIEWS IMMUNOLOGY, 2010, 10 (12) :849-859

[4] What Do Autoinflammatory Syndromes Teach About Common Cutaneous Diseases Such as Pyoderma Gangrenosum? A Commentary [J].

Butler, Daniel ;

Shinkai, Kanade .

DERMATOLOGIC CLINICS, 2013, 31 (03) :427-+

[5] The comparative effects of tacrolimus and hydrocortisone in adult atopic dermatitis: an immunohistochemical study [J].

Caproni, M. ;

Torchia, D. ;

Antiga, E. ;

Terranova, M. ;

Volpi, W. ;

Del Bianco, E. ;

D'Agata, A. ;

Fabbri, P. .

BRITISH JOURNAL OF DERMATOLOGY, 2007, 156 (02) :312-319

[6] The effects of tacrolimus ointment on regulatory T lymphocytes in atopic dermatitis [J].

Caproni, Marzia ;

Torchia, Daniele ;

Antiga, Emiliano ;

Volpi, Walter ;

Del Bianco, Elena ;

Fabbri, Paolo .

JOURNAL OF CLINICAL IMMUNOLOGY, 2006, 26 (04) :370-375

[7] Genotype, phenotype, and clinical course in five patients with PAPA syndrome (pyogenic sterile arthritis, pyoderma gangrenosum, and acne) [J].

Demidowich, Andrew P. ;

Freeman, Alexandra F. ;

Kuhns, Douglas B. ;

Aksentijevich, Ivona ;

Gallin, John I. ;

Turner, Maria L. ;

Kastner, Daniel L. ;

Holland, Steven M. .

ARTHRITIS AND RHEUMATISM, 2012, 64 (06) :2022-2027

[8] Foxp3+ Regulatory T Cells, Th17 Effector Cells, and Cytokine Environment in Inflammatory Bowel Disease [J].

Eastaff-Leung, Nicola ;

Mabarrack, Nicholas ;

Barbour, Angela ;

Cummins, Adrian ;

Barry, Simon .

JOURNAL OF CLINICAL IMMUNOLOGY, 2010, 30 (01) :80-89

[9] Inflammatory Bowel Disease and Mutations Affecting the Interleukin-10 Receptor [J].

Glocker, Erik-Oliver ;

Kotlarz, Daniel ;

Boztug, Kaan ;

Gertz, E. Michael ;

Schaeffer, Alejandro A. ;

Noyan, Fatih ;

Perro, Mario ;

Diestelhorst, Jana ;

Allroth, Anna ;

Murugan, Dhaarini ;

Haetscher, Nadine ;

Pfeifer, Dietmar ;

Sykora, Karl-Walter ;

Sauer, Martin ;

Kreipe, Hans ;

Lacher, Martin ;

Nustede, Rainer ;

Woellner, Cristina ;

Baumann, Ulrich ;

Salzer, Ulrich ;

Koletzko, Sibylle ;

Shah, Neil ;

Segal, Anthony W. ;

Sauerbrey, Axel ;

Buderus, Stephan ;

Snapper, Scott B. ;

Grimbacher, Bodo ;

Klein, Christoph .

NEW ENGLAND JOURNAL OF MEDICINE, 2009, 361 (21) :2033-2045

[10] Severely recalcitrant pyoderma gangrenosum successfully treated with ustekinumab [J].

Goldminz, Ari M. ;

Botto, Nina C. ;

Gottlieb, Alice B. .

JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY, 2012, 67 (05) :E237-E238

← 1 2 →