Management of the ACC/AHA Stage D Patient: Cardiac Transplantation

被引:12
作者
Kittleson, Michelle M. [1 ]
Kobashigawa, Jon A. [1 ]
机构
[1] Cedars Sinai Heart Inst, Div Cardiol, Los Angeles, CA USA
关键词
Cardiac transplantation; End-stage heart failure; Rejection; Immunosuppression; CORONARY-ARTERY-DISEASE; ACUTE MYOCARDIAL-INFARCTION; INTRAVASCULAR ULTRASOUND; HEART-TRANSPLANTATION; MYCOPHENOLATE-MOFETIL; INTERNATIONAL SOCIETY; CARDIOVASCULAR MORTALITY; ENDOMYOCARDIAL BIOPSY; ALLOGRAFT-REJECTION; SINGLE-CENTER;
D O I
10.1016/j.ccl.2013.09.004
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Over the last 4 decades, cardiac transplantation has become the preferred therapy for select patients with end-stage heart disease. Heart transplantation is indicated in patients with heart failure despite optimal medical and device therapy, manifesting as intractable angina, refractory heart failure, or intractable ventricular arrhythmias. This article provides an overview of heart transplantation in the current era, focusing on the evaluation process for heart transplantation, the physiology of the transplanted heart, immunosuppressive regimens, and early and long-term complications.
引用
收藏
页码:95 / +
页数:19
相关论文
共 65 条
  • [1] Cardiac transplant vasculopathy
    Aranda, JM
    Hill, J
    [J]. CHEST, 2000, 118 (06) : 1792 - 1800
  • [2] Morphologic observations in the epicardial coronary arteries and their surroundings late after cardiac transplantation (allograft vascular disease)
    Arbustini, E
    Roberts, WC
    [J]. AMERICAN JOURNAL OF CARDIOLOGY, 1996, 78 (07) : 814 - 820
  • [3] Clinician's Guide to Cardiopulmonary Exercise Testing in Adults A Scientific Statement From the American Heart Association
    Balady, Gary J.
    Arena, Ross
    Sietsema, Kathy
    Myers, Jonathan
    Coke, Lola
    Fletcher, Gerald F.
    Forman, Daniel
    Franklin, Barry
    Guazzi, Marco
    Gulati, Martha
    Keteyian, Steven J.
    Lavie, Carl J.
    Macko, Richard
    Mancini, Donna
    Milani, Richard V.
    [J]. CIRCULATION, 2010, 122 (02) : 191 - 225
  • [4] BARALDIJUNKINS C, 1993, J HEART LUNG TRANSPL, V12, P63
  • [5] A Prospective, Randomized Trial of Single-Drug Versus Dual-Drug Immunosuppression in Heart Transplantation The Tacrolimus in Combination, Tacrolimus Alone Compared (TICTAC) Trial
    Baran, David A.
    Zucker, Mark J.
    Arroyo, Luis H.
    Camacho, Margarita
    Goldschmidt, Marc E.
    Nicholls, Stephen J.
    Prevost-Fernandez, Jeanne
    Carr, Candace
    Adams, Laura
    Pardi, Susan
    Hou, Vera
    Binetti, Maria
    McCahill, Jeanine
    Chichetti, Joanne
    Viloria, Valerie
    SanAgustin, Mary Gladys
    Ebuenga-Smith, Jennifer
    Mele, Leslie
    Martin, Anthony
    Blicharz, Donna
    Wolski, Kathy
    Olesnicky, Ludmilla
    Qian, Fang
    Gass, Alan L.
    Cohen, Marc
    [J]. CIRCULATION-HEART FAILURE, 2011, 4 (02) : 129 - 137
  • [6] Billingham M E, 1990, J Heart Transplant, V9, P587
  • [7] Sirolimus therapy after early cyclosporine withdrawal reduces the risk for cancer in adult renal transplantation
    Campistol, Josep M.
    Eris, Josette
    Oberbauer, Rainer
    Friend, Peter
    Hutchison, Brian
    Morales, Jose M.
    Claesson, Kerstin
    Stallone, Giovanni
    Russ, Graeme
    Rostaing, Lionel
    Kreis, Henri
    Burke, James T.
    Brault, Yves
    Scarola, Joseph A.
    Neylan, John F.
    [J]. JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY, 2006, 17 (02): : 581 - 589
  • [8] Costanzo MR, 1998, J HEART LUNG TRANSPL, V17, P744
  • [9] Noninvasive discrimination of rejection in cardiac allograft recipients using gene expression profiling
    Deng, MC
    Eisen, HJ
    Mehra, MR
    Billingham, M
    Marboe, CC
    Berry, G
    Kobashigawa, J
    Johnson, FL
    Starling, RC
    Murali, S
    Pauly, DF
    Baron, H
    Wohlgemuth, JG
    Woodward, RN
    Klingler, TM
    Walther, D
    Lal, PG
    Rosenberg, S
    Hunt, S
    [J]. AMERICAN JOURNAL OF TRANSPLANTATION, 2006, 6 (01) : 150 - 160
  • [10] Everolimus Versus Mycophenolate Mofetil in Heart Transplantation: A Randomized, Multicenter Trial
    Eisen, H. J.
    Kobashigawa, J.
    Starling, R. C.
    Pauly, D. F.
    Kfoury, A.
    Ross, H.
    Wang, S. -S.
    Cantin, B.
    Van Bakel, A.
    Ewald, G.
    Hirt, S.
    Lehmkuhl, H.
    Keogh, A.
    Rinaldi, M.
    Potena, L.
    Zuckermann, A.
    Dong, G.
    Cornu-Artis, C.
    Lopez, P.
    [J]. AMERICAN JOURNAL OF TRANSPLANTATION, 2013, 13 (05) : 1203 - 1216