The advances of electromigration techniques applied for alkaloid analysis

被引:7
作者
Dziomba, Szymon [1 ]
Belka, Mariusz [1 ]
Kowalski, Piotr [1 ]
Plenis, Alina [1 ]
Baczek, Tomasz [1 ]
机构
[1] Med Univ Gdansk, Dept Pharmaceut Chem, PL-80416 Gdansk, Poland
关键词
alkaloids; capillary electrophoresis; microchip electrophoresis; extraction; on-line preconcentration techniques; MICELLAR ELECTROKINETIC CHROMATOGRAPHY; CAPILLARY-ZONE-ELECTROPHORESIS; AMPLIFIED SAMPLE INJECTION; CONTACTLESS CONDUCTIVITY DETECTION; SELECTIVE EXHAUSTIVE INJECTION; SIMULTANEOUS CHIRAL SEPARATION; INDUCED FLUORESCENCE DETECTION; MICROWAVE-ASSISTED EXTRACTION; TRADITIONAL CHINESE MEDICINES; LIQUID-PHASE MICROEXTRACTION;
D O I
10.1002/bmc.2967
中图分类号
Q5 [生物化学];
学科分类号
071010 ; 081704 ;
摘要
Alkaloids are natural products of metabolism found mainly in plants. Their diversified pharmacological activities as medical agents and extensive occurrence in nutritional products demand the development of reliable and sensitive analytical tools. This review presents the developments in the field of electromigration techniques and specifically capillary and microchip electrophoresis. We include the main aspects of interest to researches over the past 12 years. The scope of this review covers detection, on- and off-line preconcentration techniques, chiral separation and developments in the field of microchip electrophoresis. Their applications in alkaloid determination, capillary electrochromatography and inter-molecular interactions are also examined. Copyright (c) 2013 John Wiley & Sons, Ltd.
引用
收藏
页码:1312 / 1338
页数:27
相关论文
共 149 条
  • [1] Analysis of illicit drugs by nonaqueous capillary electrophoresis and electrochemical detection
    Backofen, U
    Matysik, FM
    Hoffmann, W
    Lunte, CE
    [J]. FRESENIUS JOURNAL OF ANALYTICAL CHEMISTRY, 2000, 367 (04): : 359 - 363
  • [2] CE-electrochemiluminescence with ionic liquid for the facile separation and determination of diester-diterpenoid aconitum alkaloids in traditional Chinese herbal medicine
    Bao, Yi
    Yang, Fan
    Yang, Xiurong
    [J]. ELECTROPHORESIS, 2011, 32 (12) : 1515 - 1521
  • [3] Optimization of the separation of Vinca alkaloids by nonaqueous capillary electrophoresis
    Barthe, L
    Ribet, JP
    Pélissou, M
    Degude, MJ
    Fahy, J
    Duflos, A
    [J]. JOURNAL OF CHROMATOGRAPHY A, 2002, 968 (1-2) : 241 - 250
  • [4] Determination of inorganic cations and anions in single plant cells by capillary zone electrophoresis
    Bazzanella, A
    Lochmann, H
    Tomos, AD
    Bächmann, K
    [J]. JOURNAL OF CHROMATOGRAPHY A, 1998, 809 (1-2) : 231 - 239
  • [5] Belardi R.P., 1989, WATER POLLUT RES J C, V24, P179, DOI DOI 10.2166/WQRJ.1989.010
  • [6] Rapid quantitative determination of ephedra alkaloids in tablet formulations and human urine by microchip electrophoresis
    Belder, Detlev
    Tolba, Kamal
    Nagl, Stefan
    [J]. ELECTROPHORESIS, 2011, 32 (3-4) : 440 - 447
  • [7] Impurity profiling of atropine sulfate by microemulsion electrokinetic chromatography
    Bitar, Yaser
    Holzgrabe, Ulrike
    [J]. JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 2007, 44 (03) : 623 - 633
  • [8] Capillary Electromigration Techniques for the Quantitative Analysis of Colchicine
    Bodoki, Ede
    Iacob, Bogdan Cezar
    Oprean, Radu
    [J]. CROATICA CHEMICA ACTA, 2011, 84 (03) : 383 - 391
  • [9] Focused microwave-assisted extraction of cocaine and benzoylecgonine from coca leaves
    Brachet, A
    Christen, P
    Veuthey, JL
    [J]. PHYTOCHEMICAL ANALYSIS, 2002, 13 (03) : 162 - 169
  • [10] Brachet A, 2001, J SEP SCI, V24, P865, DOI 10.1002/1615-9314(20011101)24:10/11<865::AID-