Immune Reactions after DMEK, DSAEK and DALK

被引：43

作者：

Steven, P. ^{[1
]}

Hos, D. ^{[1
]}

Heindl, L. M. ^{[1
]}

Bock, F. ^{[1
]}

Cursiefen, C. ^{[1
]}

机构：

[1] Univ Cologne, Zentrum Augenheilkunde, D-50937 Cologne, Germany

来源：

KLINISCHE MONATSBLATTER FUR AUGENHEILKUNDE | 2013年 / 230卷 / 05期

关键词：

cornea; pharmacology; pathology; DMEK; DSAEK; DALK; immune reactions; MEMBRANE ENDOTHELIAL KERATOPLASTY; ANTERIOR LAMELLAR KERATOPLASTY; SPLIT-CORNEA TRANSPLANTATION; GRAFT-REJECTION EPISODES; PENETRATING KERATOPLASTY; RISK;

D O I：

10.1055/s-0032-1328257

中图分类号：

R77 [眼科学];

学科分类号：

100212 ;

摘要：

Purpose: The aim of this study is to describe incidence, diagnosis and therapy for endothelial immune reactions after modern lamellar corneal transplantat surgery (DMEK, DSAEK, DALK). Methods: A PubMed-based literature review and our own clinical and experimental data are evaluated. Results: There is no longer an endothelial immune reaction after DALK for keratoconus. DMEK significantly reduces the risk for endothelial immune reactions after surgery for Fuchs dystrophy. Conclusions: Modern lamellar corneal transplant techniques such as DALK and DMEK have nearly abolished the risk for endothelial immune reactions in the avascular recipient bed.

引用

页码：494 / 499

页数：6

共 26 条

[1] Risk of Corneal Transplant Rejection Significantly Reduced with Descemet's Membrane Endothelial Keratoplasty [J].

Anshu, Arundhati ;

Price, Marianne O. ;

Price, Francis W., Jr. .

OPHTHALMOLOGY, 2012, 119 (03) :536-540

[2]

Cursiefen C, 2011, OPHTHALMOLOGE, V108, P833, DOI 10.1007/s00347-011-2331-z

[3]

Cursiefen C, 2010, OPHTHALMOLOGE, V107, P370, DOI 10.1007/s00347-010-2155-2

[4] Descemet's stripping automated endothelial keratoplasty (DSAEK) [J].

Cursiefen, C. ;

Kruse, F. E. .

OPHTHALMOLOGE, 2009, 106 (10) :939-952

[5]

Cursiefen C, 2011, ARVO, V1155, pD937

[6]

Cursiefen Claus, 2007, Chem Immunol Allergy, V92, P50, DOI 10.1159/000099253

[7] Cutting Edge: Lymphatic Vessels, Not Blood Vessels, Primarily Mediate Immune Rejections After Transplantation [J].

Dietrich, Tina ;

Bock, Felix ;

Yuen, Don ;

Hos, Deniz ;

Bachmann, Bjoern O. ;

Zahn, Grit ;

Wiegand, Stanley ;

Chen, Lu ;

Cursiefen, Claus .

JOURNAL OF IMMUNOLOGY, 2010, 184 (02) :535-539

[8] Split-Cornea Transplantation - A Novel Concept to Reduce Corneal Donor Shortage [J].

Heindl, L. M. ;

Cursiefen, C. .

KLINISCHE MONATSBLATTER FUR AUGENHEILKUNDE, 2012, 229 (06) :608-614

[9] Split Cornea Transplantation for 2 Recipients - Review of the First 100 Consecutive Patients [J].

Heindl, Ludwig M. ;

Riss, Stephan ;

Laaser, Kathrin ;

Bachmann, Bjoern O. ;

Kruse, Friedrich E. ;

Cursiefen, Claus .

AMERICAN JOURNAL OF OPHTHALMOLOGY, 2011, 152 (04) :523-532

[10] Split Cornea Transplantation for 2 Recipients A New Strategy to Reduce Corneal Tissue Cost and Shortage [J].

Heindl, Ludwig M. ;

Riss, Stephan ;

Bachmann, Bjoern O. ;

Laaser, Kathrin ;

Kruse, Friedrich E. ;

Cursiefen, Claus .

OPHTHALMOLOGY, 2011, 118 (02) :294-301

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