The global, regional, and national early-onset colorectal cancer burden and trends from 1990 to 2019: results from the Global Burden of Disease Study 2019

被引:58
作者
Pan, Hongfeng [1 ,2 ]
Zhao, Zeyi [1 ,2 ]
Deng, Yu [1 ,2 ]
Zheng, Zhifang [1 ,2 ]
Huang, Ying [1 ,2 ]
Huang, Shenghui [1 ,2 ]
Chi, Pan [1 ,2 ]
机构
[1] Fujian Med Univ Union Hosp, Dept Colorectal Surg, 29 Xinquan Rd, Fuzhou 350001, Fujian, Peoples R China
[2] Fujian Med Univ Union Hosp, Dept Gen Surg, 29 Xinquan Rd, Fuzhou 350001, Fujian, Peoples R China
关键词
Early-onset colorectal cancer (EO-CRC); Incidence; Prevalence; Mortality; Disability-adjusted life years (DALYs); Global Burden of Disease (GBD); RISK-FACTORS; ASSOCIATION; SURVIVAL; GENDER;
D O I
10.1186/s12889-022-14274-7
中图分类号
R1 [预防医学、卫生学];
学科分类号
1004 ; 120402 ;
摘要
Purpose The incidence of early-onset colorectal cancer (EO-CRC), which occurs in people under age 50, has been increasing annually. The aim of this study was to provide an up-to-date estimate of the global EO-CRC burden. Methods We used Global Burden of Disease Study data and methodologies to describe changes in the EO-CRC burden from 1990 to 2019, including incidence, prevalence, mortality, and disability-adjusted life years (DALYs). The driving factors for cancer burden variation were further analyzed using decomposition analysis. Frontier analysis was used to visually demonstrate the potential for burden reduction in each country or region based on their development levels. Results The global EO-CRC incidence more than doubled, increasing from 95,737 (95% uncertainty interval (UI): 90,838-101.042) /100,000 in 1990 to 226,782 (95% UI: 207,495-248,604) /100,000 in 2019. Additionally, related deaths increased from 50,997 (95% UI: 47,692-54,410) /100,000 to 87,014 (95% UI: 80,259-94,339) /100,000, and DALYs increased from 256,1842 (95% UI: 239,4962-2,735,823) /100,000 to 4,297,573 (95% UI: 3,965,485-4,650,790) /100,000. Regarding age-standardized rates, incidence and prevalence increased significantly, while mortality and DALYs rate were basically unchanged. Decomposition analysis showed a significant increase in DALYs in the middle sociodemographic index (SDI) quintile region, in which aging and population growth played a major driving role. Frontier analysis showed that countries or regions with a higher SDI quintile tend to have greater improvement potential. Conclusion The current EO-CRC burden was found to be the greatest in the high-middle SDI quintile region and East Asia, which may need to adjust screening guidelines accordingly and introduce more effective interventions.
引用
收藏
页数:17
相关论文
共 38 条
  • [1] The global, regional, and national burden of inflammatory bowel disease in 195 countries and territories, 1990-2017: a systematic analysis for the Global Burden of Disease Study 2017
    Alatab, Sudabeh
    Sepanlou, Sadaf G.
    Ikuta, Kevin
    Vahedi, Homayoon
    Bisignano, Catherine
    Safiri, Saeid
    Sadeghi, Anahita
    Nixon, Molly R.
    Abdoli, Amir
    Abolhassani, Hassan
    Alipour, Vahid
    Almadi, Majid A. H.
    Almasi-Hashiani, Amir
    Anushiravani, Amir
    Arabloo, Jalal
    Atique, Suleman
    Awasthi, Ashish
    Badawi, Alaa
    Baig, Atif A. A.
    Bhala, Neeraj
    Bijani, Ali
    Biondi, Antonio
    Borzi, Antonio M.
    Burke, Kristin E.
    Carvalho, Felix
    Daryani, Ahmad
    Dubey, Manisha
    Eftekhari, Aziz
    Fernandes, Eduarda
    Fernandes, Joao C.
    Fischer, Florian
    Haj-Mirzaian, Arvin
    Haj-Mirzaian, Arya
    Hasanzadeh, Amir
    Hashemian, Maryam
    Hay, Simon, I
    Hoang, Chi L.
    Househ, Mowafa
    Ilesanmi, Olayinka S.
    Balalami, Nader Jafari
    James, Spencer L.
    Kengne, Andre P.
    Malekzadeh, Masoud M.
    Merat, Shahin
    Meretoja, Tuomo J.
    Mestrovic, Tomislav
    Mirrakhimov, Erkin M.
    Mirzaei, Hamed
    Mohammad, Karzan A.
    Mokdad, Ali H.
    [J]. LANCET GASTROENTEROLOGY & HEPATOLOGY, 2020, 5 (01): : 17 - 30
  • [2] Barber RM, 2017, LANCET, V390, P231, DOI [10.1016/S0140-6736(17)30818-8, 10.1016/s0140-6736(17)30818-8]
  • [3] Association between adherence to National Comprehensive Cancer Network treatment guidelines and improved survival in patients with colon cancer
    Boland, Genevieve M.
    Chang, George J.
    Haynes, Alex B.
    Chiang, Yi-Ju
    Chagpar, Ryaz
    Xing, Yan
    Hu, Chung-Yuan
    Feig, Barry W.
    You, Y. Nancy
    Cormier, Janice N.
    [J]. CANCER, 2013, 119 (08) : 1593 - 1601
  • [4] Clinicopathologic and molecular features of sporadic early-onset colorectal adenocarcinoma: an adenocarcinoma with frequent signet ring cell differentiation, rectal and sigmoid involvement, and adverse morphologic features
    Chang, Daniel T.
    Pai, Rish K.
    Rybicki, Lisa A.
    Dimaio, Michael A.
    Limaye, Maneesha
    Jayachandran, Priya
    Koong, Albert C.
    Kunz, Pamela A.
    Fisher, George A.
    Ford, James M.
    Welton, Mark
    Shelton, Andrew
    Ma, Lisa
    Arber, Daniel A.
    Pai, Reetesh K.
    [J]. MODERN PATHOLOGY, 2012, 25 (08) : 1128 - 1139
  • [5] The Global Burden of Leukemia and Its Attributable Factors in 204 Countries and Territories: Findings from the Global Burden of Disease 2019 Study and Projections to 2030
    Du, Mengbao
    Chen, Weiwei
    Liu, Ke
    Wang, Limengmeng
    Hu, Yihan
    Mao, Yingying
    Sun, Xiaohui
    Luo, Yi
    Shi, Jimin
    Shao, Keding
    Huang, He
    Ye, Ding
    [J]. JOURNAL OF ONCOLOGY, 2022, 2022
  • [6] Annual Report to the Nation on the Status of Cancer, 1975-2006, Featuring Colorectal Cancer Trends and Impact of Interventions (Risk Factors, Screening, and Treatment) to Reduce Future Rates
    Edwards, Brenda K.
    Ward, Elizabeth
    Kohler, Betsy A.
    Eheman, Christie
    Zauber, Ann G.
    Anderson, Robert N.
    Jemal, Ahmedin
    Schymura, Maria J.
    Lansdorp-Vogelaar, Iris
    Seeff, Laura C.
    van Ballegooijen, Marjolein
    Goede, S. Luuk
    Ries, Lynn A. G.
    [J]. CANCER, 2010, 116 (03) : 544 - 573
  • [7] Early-onset colorectal cancer: initial clues and current views
    Hofseth, Lorne J.
    Hebert, James R.
    Chanda, Anindya
    Chen, Hexin
    Love, Bryan L.
    Pena, Maria M.
    Murphy, E. Angela
    Sajish, Mathew
    Sheth, Amit
    Buckhaults, Phillip J.
    Berger, Franklin G.
    [J]. NATURE REVIEWS GASTROENTEROLOGY & HEPATOLOGY, 2020, 17 (06) : 352 - 364
  • [8] Sex differences in human adipose tissues - the biology of pear shape
    Karastergiou, Kalypso
    Smith, Steven R.
    Greenberg, Andrew S.
    Fried, Susan K.
    [J]. BIOLOGY OF SEX DIFFERENCES, 2012, 3
  • [9] Global burden of colorectal cancer: emerging trends, risk factors and prevention strategies
    Keum, NaNa
    Giovannucci, Edward
    [J]. NATURE REVIEWS GASTROENTEROLOGY & HEPATOLOGY, 2019, 16 (12) : 713 - 732
  • [10] Khan Naveed Ali, 2015, Asian Pac J Cancer Prev, V16, P7967