Sensitivity-enhanced and noise-reduced surface plasmon resonance sensing with microwell chips

被引：3
作者：
Pang, Kai [1 ]
Dong, Wei [1 ]
Zhang, Bing [1 ]
Zhan, Shuyue [2 ]
Wang, Xiaoping [1 ]
机构：
[1] Zhejiang Univ, Dept Opt Engn, State Key Lab Modern Opt Instrumentat, Hangzhou 310027, Peoples R China
[2] Zhejiang Univ, Ocean Coll, Hangzhou 310058, Zhejiang, Peoples R China
来源：
MEASUREMENT SCIENCE AND TECHNOLOGY | 2015年 / 26卷 / 08期
基金：
中国国家自然科学基金; 中国博士后科学基金;
关键词：
surface plasmon resonance; sensitivity enhancement; noise reduction; sensor chip; microwell chip; OPTICAL-FIBER; SENSORS;
D O I：
10.1088/0957-0233/26/8/085104
中图分类号：
T [工业技术];
学科分类号：
08 ;
摘要：
In this paper, we study a surface plasmon resonance (SPR) sensor with a microwell chip that is aimed at improving the sensitivity and reducing the noise. We present both theoretical simulations and experimental results obtained for the proposed structure. In comparison to most SPR sensors that use planar gold films, this proposed well structure enables a sensitivity enhancement of 128%. By confining the surface plasmon wave (SPW) within the well, we are able to reduce the noise by more than twice. The increased sensitivity and lower noise makes our proposed novel microwell chip suitable for small molecule or trace amount detection.
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页数：8
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