Microtubule nucleation at the centrosome and beyond

被引：118

作者：

Petry, Sabine ^{[1
]}

Vale, Ronald D. ^{[2
,3
]}

机构：

[1] Princeton Univ, Dept Mol Biol, Princeton, NJ 08540 USA

[2] Univ Calif San Francisco, Dept Cellular & Mol Pharmacol, San Francisco, CA 94158 USA

[3] Univ Calif San Francisco, Howard Hughes Med Inst, San Francisco, CA 94158 USA

来源：

NATURE CELL BIOLOGY | 2015年 / 17卷 / 09期

关键词：

TUBULIN RING COMPLEX; XENOPUS EGG EXTRACTS; GAMMA-TUBULIN; ORGANIZING CENTERS; MITOTIC SPINDLE; GOLGI-COMPLEX; AUGMIN; CELLS; ORGANIZATION; RECRUITMENT;

D O I：

10.1038/ncb3220

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

The overall organization of the microtubule cytoskeleton depends critically on where and when new microtubules are nucleated. Here we review recent work on factors that are involved in localizing and potentially activating gamma-tubulin, the key microtubule nucleating protein.

引用

页码：1089 / 1093

页数：5

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