Microtubule nucleation at the centrosome and beyond

被引：118

作者：

Petry, Sabine ^{[1
]}

Vale, Ronald D. ^{[2
,3
]}

机构：

[1] Princeton Univ, Dept Mol Biol, Princeton, NJ 08540 USA

[2] Univ Calif San Francisco, Dept Cellular & Mol Pharmacol, San Francisco, CA 94158 USA

[3] Univ Calif San Francisco, Howard Hughes Med Inst, San Francisco, CA 94158 USA

来源：

NATURE CELL BIOLOGY | 2015年 / 17卷 / 09期

关键词：

TUBULIN RING COMPLEX; XENOPUS EGG EXTRACTS; GAMMA-TUBULIN; ORGANIZING CENTERS; MITOTIC SPINDLE; GOLGI-COMPLEX; AUGMIN; CELLS; ORGANIZATION; RECRUITMENT;

D O I：

10.1038/ncb3220

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

The overall organization of the microtubule cytoskeleton depends critically on where and when new microtubules are nucleated. Here we review recent work on factors that are involved in localizing and potentially activating gamma-tubulin, the key microtubule nucleating protein.

引用

页码：1089 / 1093

页数：5

共 75 条

[31] Microtubule nucleating γ-TuSC assembles structures with 13-fold microtubule-like symmetry [J].

Kollman, Justin M. ;

Polka, Jessica K. ;

Zelter, Alex ;

Davis, Trisha N. ;

Agard, David A. .

NATURE, 2010, 466 (7308) :879-U114

[32] HAUS, the 8-Subunit Human Augmin Complex, Regulates Centrosome and Spindle Integrity [J].

Lawo, Steffen ;

Bashkurov, Mikhail ;

Mullin, Michael ;

Ferreria, Mariana Gomez ;

Kittler, Ralf ;

Habermann, Bianca ;

Tagliaferro, Andrea ;

Poser, Ina ;

Hutchins, James R. A. ;

Hegemann, Bjoern ;

Pinchev, Deborah ;

BuchholZ, Frank ;

Peters, Jan-Michael ;

Hyman, Anthony A. ;

Gingras, Anne-Claude ;

Pelletier, Laurence .

CURRENT BIOLOGY, 2009, 19 (10) :816-826

[33] Cell-cycle dependent phosphorylation of yeast pericentrin regulates γ-TuSC-mediated microtubule nucleation [J].

Lin, Tien-chen ;

Neuner, Annett ;

Schlosser, Yvonne T. ;

Scharf, Annette N. D. ;

Weber, Lisa ;

Schiebel, Elmar .

ELIFE, 2014, 3

[34] Xenopus NEDD1 is required for microtubule organization in Xenopus egg extracts [J].

Liu, Lingling ;

Wiese, Christiane .

JOURNAL OF CELL SCIENCE, 2008, 121 (05) :578-589

[35] NME7 is a functional component of the γ-tubulin ring complex [J].

Liu, Pengfei ;

Choi, Yuk-Kwan ;

Qi, Robert Z. .

MOLECULAR BIOLOGY OF THE CELL, 2014, 25 (13) :2017-2025

[36] Augmin Triggers Microtubule-Dependent Microtubule Nucleation in Interphase Plant Cells [J].

Liu, Ting ;

Tian, Juan ;

Wang, Guangda ;

Yu, Yanjun ;

Wang, Chaofeng ;

Ma, Yinping ;

Zhang, Xiaxia ;

Xia, Guixian ;

Liu, Bo ;

Kong, Zhaosheng .

CURRENT BIOLOGY, 2014, 24 (22) :2708-2713

[37] GCP-WD is a γ-tubulin targeting factor required for centrosomal and chromatin-mediated microtubule nucleation [J].

Lüders, J ;

Patel, UK ;

Stearns, T .

NATURE CELL BIOLOGY, 2006, 8 (02) :137-U10

[38] Activation of the γ-Tubulin Complex by the Mto1/2 Complex [J].

Lynch, Eric M. ;

Groocock, Lynda M. ;

Borek, Weronika E. ;

Sawin, Kenneth E. .

CURRENT BIOLOGY, 2014, 24 (08) :896-903

[39] PURIFICATION OF A CORTICAL COMPLEX CONTAINING 2 UNCONVENTIONAL ACTINS FROM ACANTHAMOEBA BY AFFINITY-CHROMATOGRAPHY ON PROFILIN-AGAROSE [J].

MACHESKY, LM ;

ATKINSON, SJ ;

AMPE, C ;

VANDEKERCKHOVE, J ;

POLLARD, TD .

JOURNAL OF CELL BIOLOGY, 1994, 127 (01) :107-115

[40] Making microtubules and mitotic spindles in cells without functional centrosomes [J].

Mahoney, NM ;

Goshima, G ;

Douglass, AD ;

Vale, RD .

CURRENT BIOLOGY, 2006, 16 (06) :564-569

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