Cholesterol-lowering effects of lactic acid bacteria isolated from Musa sapientum Linn

被引：0
作者：
Rattanachak, Nontaporn [1 ]
Nualsri, Chatchawin [2 ]
Nittayasut, Naiyaphat [3 ]
Srisayam, Montra [1 ]
Chodnakarin, Arunluk [1 ]
Wongkaewkhiaw, Saharut [4 ]
机构：
[1] Pibulsongkram Rajabhat Univ, Fac Sci & Technol, Phitsanulok 65000, Thailand
[2] Pibulsongkram Rajabhat Univ, Fac Food & Agr Technol, Phitsanulok 65000, Thailand
[3] Chulalongkorn Univ, Fac Vet Sci, Dept Vet Microbiol, Bangkok 10330, Thailand
[4] King Mongkuts Inst Technol Ladkrabang, Sch Dent, Bangkok 10520, Thailand
来源：
MAEJO INTERNATIONAL JOURNAL OF SCIENCE AND TECHNOLOGY | 2022年 / 16卷 / 03期
关键词：
lactic acid bacteria; cholesterol-lowering property; Musa sapientum Linn; FERMENTED MILK; IN-VITRO; STRAINS; LACTOBACILLUS; RESISTANCE; STARTER; SUSCEPTIBILITY; METABOLISM; ORIGIN; FLOUR;
D O I：
暂无
中图分类号：
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号：
07 ; 0710 ; 09 ;
摘要：
Hypercholesterolemia is generally recognised as a risk factor for cardiovascular disease. Musa sapientum Linn. or Kluai Namwa (banana; ABB genome type) provides a functional nutrient in health promotion products and is a source of various probiotics. Lactic acid bacteria (LAB) isolated from several sources are reported with cholesterol-lowering potential. However, the effects of LAB isolated from bananas on total cholesterol are still unknown. The aim of this study is to investigate the cholesterol-removing ability of 5 LAB strains isolated from raw M. sapientum. All tested strains show a cholesterol-lowering property in species-and strain-dependent manner, with Weissella paramesenteroides NR27 being the most effective probiotic in reducing cholesterol concentration (P < 0.001). The removal of cholesterol by LAB is partially due to the production of bile salt hydrolase. All tested isolates exhibit more than 75% and 50% survival rates after challenging with simulated gastric and intestinal fluids respectively. Of these, W. paramesenteroides NR27 has a significantly higher survival rate (80%) in gastrointestinal conditions (P < 0.001), compared with all tested strains. In addition, antibiotic-resistant genes are not present in all drugs tested on this isolate. Therefore, W. paramesenteroides NR27 could be a promising probiotic candidate for reducing total cholesterol.
引用
收藏
页码：249 / 261
页数：13
相关论文
共 45 条
[21]  
Kumar K. P. S., 2012, J PHARMACOG PHYTOCHE, V1, P51
[22]  
Lim Hyeong-Jun, 2004, J Vet Sci, V5, P391
[23]   Removal of cholesterol by lactobacilli via incorporation and conversion to coprostanol [J].
Lye, H. -S. ;
Rusul, G. ;
Liong, M. -T. .
JOURNAL OF DAIRY SCIENCE, 2010, 93 (04) :1383-1392
[24]   Screening for Cholesterol-Lowering Probiotics from Lactic Acid Bacteria Isolated from Corn Silage Based on Three Hypothesized Pathways [J].
Ma, Changlu ;
Zhang, Shuwen ;
Lu, Jing ;
Zhang, Cai ;
Pang, Xiaoyang ;
Lv, Jiaping .
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2019, 20 (09)
[25]   Towards understanding molecular modes of probiotic action [J].
Marco, ML ;
Pavan, S ;
Kleerebezem, M .
CURRENT OPINION IN BIOTECHNOLOGY, 2006, 17 (02) :204-210
[26]   The effects of Lactobacillus plantarum on small intestinal barrier function and mucosal gene transcription; a randomized double-blind placebo controlled trial [J].
Mujagic, Zlatan ;
de Vos, Paul ;
Boekschoten, Mark V. ;
Govers, Coen ;
Pieters, Harm-Jan H. M. ;
de Wit, Nicole J. W. ;
Bron, Peter A. ;
Masclee, Ad A. M. ;
Troost, Freddy J. .
SCIENTIFIC REPORTS, 2017, 7
[27]   Characterization and Transfer of Antibiotic Resistance in Lactic Acid Bacteria from Fermented Food Products [J].
Nawaz, Muhammad ;
Wang, Juan ;
Zhou, Aiping ;
Ma, Chaofeng ;
Wu, Xiaokang ;
Moore, John E. ;
Millar, B. Cherie ;
Xu, Jiru .
CURRENT MICROBIOLOGY, 2011, 62 (03) :1081-1089
[28]   Multiplex PCR for the detection of tetracycline resistant genes [J].
Ng, LK ;
Martin, I ;
Alfa, M ;
Mulvey, M .
MOLECULAR AND CELLULAR PROBES, 2001, 15 (04) :209-215
[29]   Resistance of potential probiotic lactic acid bacteria and bifidobacteria of African and European origin to antimicrobials: Determination and transferability of the resistance genes to other bacteria [J].
Ouoba, Labia Irene Ivette ;
Lei, Vicki ;
Jensen, Lars B. .
INTERNATIONAL JOURNAL OF FOOD MICROBIOLOGY, 2008, 121 (02) :217-224
[30]   In vitro screening of lactic acid bacteria for multi-strain probiotics [J].
Pringsulaka, O. ;
Rueangyotchanthana, K. ;
Suwannasai, N. ;
Watanapokasin, R. ;
Amnueysit, P. ;
Sunthornthummas, S. ;
Sukkhum, S. ;
Sarawaneeyaruk, S. ;
Rangsiruji, A. .
LIVESTOCK SCIENCE, 2015, 174 :66-73
12345