Implications for programming strategy of the location of the active contact in subthalamic nucleus deep brain stimulation

被引:10
作者
Connolly, Patrick J. [1 ]
Halpern, Casey H. [2 ]
Baltuch, Gordon H. [2 ]
Danish, Shabbar F. [3 ]
Jaggi, Jurg L. [2 ]
机构
[1] Temple Univ, Dept Neurosurg, Philadelphia, PA 19140 USA
[2] Univ Penn, Dept Neurosurg, Philadelphia, PA 19104 USA
[3] Univ Med & Dent New Jersey, Robert Wood Johnson Med Sch, New Brunswick, NJ USA
关键词
Deep brain stimulation; Subthalamic nucleus; Programming; Targeting; PARKINSONS-DISEASE; IMPLANTATION; MRI;
D O I
10.1016/j.jocn.2011.12.002
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
We aimed to determine whether our targeting method for the subthalamic nucleus (STN) in Parkinson's disease informs the initial programming sequence. We evaluated 100 STN-lead pairs from 50 patients who underwent bilateral STN-deep brain stimulation operations. All patients had at least one year of follow-up. In each patient, we measured coordinates of the STN borders and determined the center from special T2-weighted MRI. We then measured the postoperative location of the lead tip by MRI registered to preoperative images. Finally, we determined the mode and active contact(s). Programming was monopolar 71% of the time. A total of 52% of left and 72% of right STN active contacts were located posterolateral to the STN center. In z, only 14% of the active contact(s) were >1 mm below the STN center. Contacts 1 or 2 were active 90% of the time. The consistent location of active contacts suggests that initial programming began with contact 1 or 2. (C) 2011 Elsevier Ltd. All rights reserved.
引用
收藏
页码:1029 / 1031
页数:3
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