Nucleosome formation potential of exons, introns, and Alu repeats

被引:19
作者
Levitsky, VG [1 ]
Podkolodnaya, OA [1 ]
Kolchanov, NA [1 ]
Podkolodny, NL [1 ]
机构
[1] Inst Cytol & Genet, Lab Theoret Genet, Novosibirsk 630090, Russia
基金
俄罗斯基础研究基金会;
关键词
D O I
10.1093/bioinformatics/17.11.1062
中图分类号
Q5 [生物化学];
学科分类号
071010 ; 081704 ;
摘要
A program for constructing nucleosome formation potential profile was applied for investigation of exons, introns, and repetitive sequences. The program is available at http: //wwwmgs.bionet.nsc.ru/mgs/programs/recon/. We have demonstrated that introns and repetitive sequences exhibit higher nucleosome formation potentials than exons. This fact may be explained by functional saturation of exons with genetic code, hindering the localization of efficient nucleosome positioning sites.
引用
收藏
页码:1062 / 1064
页数:3
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