What is in our environment that effects puberty?

被引:55
作者
Fisher, Marisa M. [1 ]
Eugster, Erica A. [1 ]
机构
[1] Indiana Univ Sch Med, Riley Hosp Children, Sect Pediat Endocrinol, Dept Pediat, Indianapolis, IN 46202 USA
关键词
Puberty timing; Endocrine disrupting chemicals; Phytoestrogens; Phthalates; Bisphenol-A; Pesticides; ENDOCRINE-DISRUPTING CHEMICALS; SECONDARY SEXUAL CHARACTERISTICS; BODY-MASS INDEX; UNITED-STATES; IN-UTERO; PRECOCIOUS PUBERTY; PHTHALATE EXPOSURE; PEDIATRIC RESEARCH; SECULAR TRENDS; FINAL HEIGHT;
D O I
10.1016/j.reprotox.2013.03.012
中图分类号
Q [生物科学];
学科分类号
07 ; 0710 ; 09 ;
摘要
Recent studies indicate that the onset of puberty is occurring at increasingly younger ages. Many etiologies have been hypothesized to be involved, but environmental exposures are among the most worrisome. Multiple organizations have endorsed the need to study and provide clinical awareness regarding the effect of a child's environment on pubertal timing. This review article summarizes the current understanding of the major environmental influences on pubertal timing, focusing on factors for which the most scientific evidence exists. The research reviewed addresses intrinsic factors unique to each individual, naturally occurring endocrine disruptors and chemical endocrine disruptors. In each category, evidence was found for and against the involvement of specific environmental factors on pubertal timing. Ultimately, an individual's environment is likely comprised of many aspects that collectively contribute to the timing of puberty. The need for research aimed at elucidating the effects of numerous specific yet disparate forms of exposures is emphasized. (C) 2013 Elsevier Inc. All rights reserved.
引用
收藏
页码:7 / 14
页数:8
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