Clinical indications for oral antidiabetics in infertility treatments, gestational diabetes and prevention of type-2 diabetes mellitus

被引:0
作者
Bühling, KJ
Bartley, J
Lübbert, H
机构
[1] Gemeinschaftspraxis BKS, Diabetol DDG, D-22767 Hamburg, Germany
[2] Univ Med Berlin, Charite, Klin Geburtsmed, Berlin, Germany
[3] Univ Med Berlin, Charite, Klin Frauenheilkunde & Geburtshilfe, Abt Gynakol Endokrinol & Reprod Med, Berlin, Germany
关键词
oral antidiabetics; pregnancy; gestational diabetes; type-2; diabetes; hyperinsulinaemia;
D O I
10.1055/s-2006-923772
中图分类号
R71 [妇产科学];
学科分类号
100211 ;
摘要
The therapy of polycystic ovarian syndrome has changed considerably in recent years due to the use of oral antidiabetics (OAD). This review gives an overview of the present indications for different OAD in fertility treatment. The use during pregnancy and post partum and the significance of hyperinsulinaemia in this context is evaluated critically.
引用
收藏
页码:258 / 262
页数:5
相关论文
共 26 条
  • [1] Troglitazone improves ovulation and hirsutism in the polycystic ovary syndrome: A multicenter, double blind, placebo-controlled trial
    Azziz, R
    Ehrmann, D
    Legro, RS
    Whitcomb, RW
    Hanley, R
    Fereshetian, AG
    O'Keefe, M
    Ghazzi, MN
    [J]. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, 2001, 86 (04) : 1626 - 1632
  • [2] BERGER A, 1996, DT ARZTEBL, V49, pA3280
  • [3] Preservation of pancreatic β-cell function and prevention of type 2 diabetes by pharmacological treatment of insulin resistance in high-risk Hispanic women
    Buchanan, TA
    Xiang, AH
    Peters, RK
    Kjos, SL
    Marroquin, A
    Goico, J
    Ochoa, C
    Tan, S
    Berkowitz, K
    Hodis, HN
    Azen, SP
    [J]. DIABETES, 2002, 51 (09) : 2796 - 2803
  • [4] Ovarian function and metabolic factors in women with oligomenorrhea treated with metformin in a randomized double blind placebo-controlled trial
    Fleming, R
    Hopkinson, ZE
    Wallace, AM
    Greer, IA
    Sattar, N
    [J]. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, 2002, 87 (02) : 569 - 574
  • [5] Sequential treatment of metformin and clomiphene citrate in clomiphene-resistant women with polycystic ovary syndrome: a randomized, controlled trial
    George, SS
    George, K
    Irwin, C
    Job, V
    Selvakumar, R
    Jeyaseelan, V
    Seshadri, MS
    [J]. HUMAN REPRODUCTION, 2003, 18 (02) : 299 - 304
  • [6] Metformin therapy throughout pregnancy reduces the development of gestational diabetes in women with polycystic ovary syndrome
    Glueck, CJ
    Wang, P
    Kobayashi, S
    Phillips, H
    Sieve-Smith, L
    [J]. FERTILITY AND STERILITY, 2002, 77 (03) : 520 - 525
  • [7] Continuing metformin throughout pregnancy in women with polycystic ovary syndrome appears to safely reduce first-trimester spontaneous abortion: a pilot study
    Glueck, CJ
    Phillips, H
    Cameron, D
    Sieve-Smith, L
    Wang, P
    [J]. FERTILITY AND STERILITY, 2001, 75 (01) : 46 - 52
  • [8] HU G, 2004, DIABETOLOGIA, V47, P1245, DOI DOI 10.1007/S00125-004-1433-4
  • [9] Comparison of glyburide and insulin for the management of gestational diabetes in a large managed care organization
    Jacobson, GF
    Ramos, GA
    Ching, JY
    Kirby, RS
    Ferrara, A
    Field, DR
    [J]. AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY, 2005, 193 (01) : 118 - 124
  • [10] Effects of metformin on early pregnancy loss in the polycystic ovary syndrome
    Jakubowicz, DJ
    Iuorno, MJ
    Jakubowicz, S
    Roberts, KA
    Nestler, JE
    [J]. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, 2002, 87 (02) : 524 - 529