Development of photopolymerized fluorescence sensor for glucose analysis

被引:20
作者
Cubuk, Soner [1 ]
Yetimoglu, Ece Kok [1 ]
Kahraman, M. Vezir [1 ]
Demirbilek, Pinar [1 ]
Firlak, Melike [2 ]
机构
[1] Marmara Univ, Dept Chem, Fac Art & Sci, Istanbul, Turkey
[2] Istanbul Kemerburgaz Univ, Sch Pharm, Istanbul, Turkey
关键词
Glucose analysis; Optical sensor; Fluorescence; Membrane; UV-curing; IMPRINTED POLYMERS; SACCHARIDES; SEPARATION; SUGARS; ARRAY;
D O I
10.1016/j.snb.2013.02.004
中图分类号
O65 [分析化学];
学科分类号
070302 ; 081704 ;
摘要
The sensing membrane was prepared by photopolymerization of 4-vinylphenylboronicacid (VPBA), hydroxyethylmethacrylate (HEMA) and poly(ethylene glycol) diacrylate (PEG-DA). The membran is capable of determining glucose between 2.78 x 10(-4) mM and 5.56 x 10(-3) mM with a limit of detection of 0.89 x 10(-5) mM, and limit of quantification 3.17 x 10(-3) mM (n = 7). It can be completely regenerated by using distilled water. The sensor performance characteristics such as response time, dynamic working range and sensitivity were reported. The proposed sensor was then applied successfully for the determination of glucose in blood samples. The optical sensor was stable, cost effective, easy to prepare, rapid and simple for the determination of glucose. (C) 2013 Elsevier B.V. All rights reserved.
引用
收藏
页码:187 / 193
页数:7
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