Biocompatibility study for PVP wound dressing obtained in different conditions

被引:94
作者
Higa, OZ [1 ]
Rogero, SO [1 ]
Machado, LDB [1 ]
Mathor, MB [1 ]
Lugao, AB [1 ]
机构
[1] IPEN, CNEN SP, BR-05422970 Sao Paulo, Brazil
关键词
biocompatibility of PVP membranes; cytotoxicity test; hemolysis;
D O I
10.1016/S0969-806X(99)00215-7
中图分类号
O64 [物理化学(理论化学)、化学物理学];
学科分类号
070304 ; 081704 ;
摘要
Hydrogels composed of PVP, PEG and agar, produced by simultaneous crosslinking and package sterilization by ionizing radiation, are used mainly as wound dressing. In this study, membranes prepared in different conditions were tested for their properties including in vitro biocompatibility. The results showed that the mechanical properties were in an acceptable range of values and that the membranes can be considered as non toxic and non hemolytic to the cells. (C) 1999 Elsevier Science Ltd. All rights reserved.
引用
收藏
页码:705 / 707
页数:3
相关论文
共 5 条
  • [1] [Anonymous], 1992, 10993 ISO
  • [2] International Organization for Standardization, 1992, 109935 ISO
  • [3] Study of wound dressing structure and hydration/dehydration properties
    Lugao, AB
    Machado, LDB
    Miranda, LF
    Alvarez, MR
    Rosiak, JM
    [J]. RADIATION PHYSICS AND CHEMISTRY, 1998, 52 (1-6) : 319 - 322
  • [4] NAKAMURA A, 1989, P JAP AT RES I JAERI, P79
  • [5] Rosiak J., 1989, United States Patent, Patent No. [4871490A, 4871490]